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Page 1
Showing results for shedding g
Search for Schedding G instead (1 results)
Illuminating G-Protein-Coupling Selectivity of GPCRs.
Inoue A, Raimondi F, Kadji FMN, Singh G, Kishi T, Uwamizu A, Ono Y, Shinjo Y, Ishida S, Arang N, Kawakami K, Gutkind JS, Aoki J, Russell RB. Inoue A, et al. Cell. 2019 Jun 13;177(7):1933-1947.e25. doi: 10.1016/j.cell.2019.04.044. Epub 2019 May 31. Cell. 2019. PMID: 31160049 Free PMC article.
Heterotrimetic G proteins consist of four subfamilies (G(s), G(i/o), G(q/11), and G(12/13)) that mediate signaling via G-protein-coupled receptors (GPCRs), principally by receptors binding Galpha C termini. ...For each receptor, we probed …
Heterotrimetic G proteins consist of four subfamilies (G(s), G(i/o), G(q/11), and G(12/13)) that mediate …
TGFalpha shedding assay: an accurate and versatile method for detecting GPCR activation.
Inoue A, Ishiguro J, Kitamura H, Arima N, Okutani M, Shuto A, Higashiyama S, Ohwada T, Arai H, Makide K, Aoki J. Inoue A, et al. Nat Methods. 2012 Oct;9(10):1021-9. doi: 10.1038/nmeth.2172. Epub 2012 Sep 16. Nat Methods. 2012. PMID: 22983457
Here we report a transforming growth factor-alpha (TGFalpha) shedding assay, in which GPCR activation is measured as ectodomain shedding of a membrane-bound proform of alkaline phosphatase-tagged TGFalpha (AP-TGFalpha) and its release into conditioned medium. AP-TGF …
Here we report a transforming growth factor-alpha (TGFalpha) shedding assay, in which GPCR activation is measured as ectodomain sh …
Viral shedding and the durability of immunoglobulin G antibodies to severe acute respiratory syndrome coronavirus 2.
Lusida MI, Gunawan E, Megasari NLA, Yamani LN, Juniastuti, Utsumi T, Mori Y. Lusida MI, et al. Microbiol Immunol. 2022 Apr;66(4):173-178. doi: 10.1111/1348-0421.12962. Epub 2022 Mar 3. Microbiol Immunol. 2022. PMID: 35007349 Free article.
We followed 45 participants in Surabaya, Indonesia, for 10 months and compared their PCR and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) results. As much as 13 out of 45 participants were IgG seropositive at least once while the rema …
We followed 45 participants in Surabaya, Indonesia, for 10 months and compared their PCR and severe acute respiratory syndrome coronavirus 2 …
Viral-induced rhinitis.
Winther B, Gwaltney JM Jr, Mygind N, Hendley JO. Winther B, et al. Am J Rhinol. 1998 Jan-Feb;12(1):17-20. doi: 10.2500/105065898782102954. Am J Rhinol. 1998. PMID: 9513654 Review.
Rhinovirus triggers an inflammatory cascade, evidenced by the presence of inflammatory mediators (e.g., IL-8) and proinflammatory cytokines (e.g., kinins) in nasal secretions, which results in symptomatic illness. ...Treatment of rhinovirus colds may require an anti …
Rhinovirus triggers an inflammatory cascade, evidenced by the presence of inflammatory mediators (e.g., IL-8) and proinflammatory cyt …
Perspectives on super-shedding of Escherichia coli O157:H7 by cattle.
Munns KD, Selinger LB, Stanford K, Guan L, Callaway TR, McAllister TA. Munns KD, et al. Foodborne Pathog Dis. 2015 Feb;12(2):89-103. doi: 10.1089/fpd.2014.1829. Epub 2014 Dec 16. Foodborne Pathog Dis. 2015. PMID: 25514549 Review.
Cattle are the primary reservoir of this bacterium, with the concentration and frequency of E. coli O157:H7 shedding varying greatly among individuals. The term "super-shedder" has been applied to cattle that shed concentrations of E. coli O157:H7 104 colony-forming units/ …
Cattle are the primary reservoir of this bacterium, with the concentration and frequency of E. coli O157:H7 shedding varying greatly …
Syndecan-1 in liver pathophysiology.
Reszegi A, Tátrai P, Regős E, Kovalszky I, Baghy K. Reszegi A, et al. Am J Physiol Cell Physiol. 2022 Aug 1;323(2):C289-C294. doi: 10.1152/ajpcell.00039.2022. Epub 2022 Jun 15. Am J Physiol Cell Physiol. 2022. PMID: 35704700 Free article. Review.
In addition, as being a hepatitis C receptor, hepatitis C virus (HCV)-infected livers produce extremely large amounts of syndecan-1. The serum levels of the cleaved (shedded) extracellular domain have clinical significance, as their increased concentration reflects on poor …
In addition, as being a hepatitis C receptor, hepatitis C virus (HCV)-infected livers produce extremely large amounts of syndecan-1. The ser …
Shedding of oral pentavalent bovine-human reassortant rotavirus vaccine indicates high uptake rate of vaccine and prominence of G-type G1.
Markkula J, Hemming-Harlo M, Vesikari T. Markkula J, et al. Vaccine. 2020 Feb 5;38(6):1378-1383. doi: 10.1016/j.vaccine.2019.12.007. Epub 2019 Dec 17. Vaccine. 2020. PMID: 31862199
RESULTS: We found that 93% of the vaccinees shed vaccine related viral particles in one sample taken 5-10 days after the first dose, indicating that stool shedding is very common and may be regarded as a marker of successful vaccination. Genotype G1 was the predominant gen …
RESULTS: We found that 93% of the vaccinees shed vaccine related viral particles in one sample taken 5-10 days after the first dose, indicat …
Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels.
Tatsumi M, Kishi T, Ishida S, Kawana H, Uwamizu A, Ono Y, Kawakami K, Aoki J, Inoue A. Tatsumi M, et al. PLoS One. 2023 Jan 20;18(1):e0280448. doi: 10.1371/journal.pone.0280448. eCollection 2023. PLoS One. 2023. PMID: 36668668 Free PMC article.
In this study, we demonstrated that a transforming growth factor alpha (TGFalpha) shedding assay, previously developed for detecting G-protein-coupled receptor (GPCR) activation, can also detect TRP channel activation. ...Mechanistically, TRP-channel-triggered TGFal …
In this study, we demonstrated that a transforming growth factor alpha (TGFalpha) shedding assay, previously developed for detecting …
Nanoparticles targeting HLA-G for gene therapy in cancer.
Zidi I, Ben Amor N. Zidi I, et al. Med Oncol. 2012 Jun;29(2):1384-90. doi: 10.1007/s12032-011-9942-8. Epub 2011 Apr 17. Med Oncol. 2012. PMID: 21499927 Review.
Cancer cells are aided by immune-tolerant functions of HLA-G to escape the immune surveillance. In general, cancer cells can express membranous HLA-G, secrete soluble HLA-G, produce HLA-G positive exosomes, and can be subjected to proteolytic cleavage …
Cancer cells are aided by immune-tolerant functions of HLA-G to escape the immune surveillance. In general, cancer cells can express …
3,469 results