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2009 2
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78 results

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Page 1
Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma.
Hamel AR, Yan W, Rouhana JM, Monovarfeshani A, Jiang X, Mehta PA, Advani J, Luo Y, Liang Q, Rajasundaram S, Shrivastava A, Duchinski K, Mantena S, Wang J, van Zyl T, Pasquale LR, Swaroop A, Gharahkhani P, Khawaja AP, MacGregor S; International Glaucoma Genetics Consortium (IGGC); Chen R, Vitart V, Sanes JR, Wiggs JL, Segrè AV. Hamel AR, et al. Nat Commun. 2024 Jan 9;15(1):396. doi: 10.1038/s41467-023-44380-y. Nat Commun. 2024. PMID: 38195602 Free PMC article.
Phenotypic and genetic characteristics of retinal vascular parameters and their association with diseases.
Ortín Vela S, Beyeler MJ, Trofimova O, Iuliani I, Vargas Quiros JD, de Vries VA, Meloni I, Elwakil A, Hoogewoud F, Liefers B, Presby D, Ramdas WD, Tomasoni M, Schlingemann R, Klaver CCW, Bergmann S. Ortín Vela S, et al. Among authors: ramdas wd. Nat Commun. 2024 Nov 6;15(1):9593. doi: 10.1038/s41467-024-52334-1. Nat Commun. 2024. PMID: 39505872 Free PMC article.
Association of Systemic Medication Use with Glaucoma and Intraocular Pressure: The European Eye Epidemiology Consortium.
Vergroesen JE, Schuster AK, Stuart KV, Asefa NG, Cougnard-Grégoire A, Delcourt C, Schweitzer C, Barreto P, Coimbra R, Foster PJ, Luben RN, Pfeiffer N, Stingl JV, Kirsten T, Rauscher FG, Wirkner K, Jansonius NM, Arnould L, Creuzot-Garcher CP, Stricker BH, Keskini C, Topouzis F, Bertelsen G, Eggen AE, Bikbov MM, Jonas JB, Klaver CCW, Ramdas WD, Khawaja AP; European Eye Epidemiology Consortium. Vergroesen JE, et al. Among authors: ramdas wd. Ophthalmology. 2023 Sep;130(9):893-906. doi: 10.1016/j.ophtha.2023.05.001. Epub 2023 May 6. Ophthalmology. 2023. PMID: 37150298 Free article.
Glaucoma Patients Have a Lower Abundance of Butyrate-Producing Taxa in the Gut.
Vergroesen JE, Jarrar ZA, Weiss S, Frost F, Ansari AS, Nguyen P, Kraaij R, Medina-Gomez C, Völzke H, Tost F, Amin N, van Duijn CM, Klaver CCW, Jürgens C, Hammond CJ, Ramdas WD. Vergroesen JE, et al. Among authors: ramdas wd. Invest Ophthalmol Vis Sci. 2024 Feb 1;65(2):7. doi: 10.1167/iovs.65.2.7. Invest Ophthalmol Vis Sci. 2024. PMID: 38315494 Free PMC article.
A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus.
Hardcastle AJ, Liskova P, Bykhovskaya Y, McComish BJ, Davidson AE, Inglehearn CF, Li X, Choquet H, Habeeb M, Lucas SEM, Sahebjada S, Pontikos N, Lopez KER, Khawaja AP, Ali M, Dudakova L, Skalicka P, Van Dooren BTH, Geerards AJM, Haudum CW, Faro VL, Tenen A, Simcoe MJ, Patasova K, Yarrand D, Yin J, Siddiqui S, Rice A, Farraj LA, Chen YI, Rahi JS, Krauss RM, Theusch E, Charlesworth JC, Szczotka-Flynn L, Toomes C, Meester-Smoor MA, Richardson AJ, Mitchell PA, Taylor KD, Melles RB, Aldave AJ, Mills RA, Cao K, Chan E, Daniell MD, Wang JJ, Rotter JI, Hewitt AW, MacGregor S, Klaver CCW, Ramdas WD, Craig JE, Iyengar SK, O'Brart D, Jorgenson E, Baird PN, Rabinowitz YS, Burdon KP, Hammond CJ, Tuft SJ, Hysi PG. Hardcastle AJ, et al. Among authors: ramdas wd. Commun Biol. 2021 Mar 1;4(1):266. doi: 10.1038/s42003-021-01784-0. Commun Biol. 2021. PMID: 33649486 Free PMC article.
Genetic Associations Between Smoking- and Glaucoma-Related Traits.
Tran JH, Stuart KV, de Vries V, Vergroesen JE, Cousins CC, Hysi PG, Do R, Rocheleau G, Kang JH, Wiggs JL, MacGregor S, Khawaja AP, Mackey DA, Klaver CCW, Ramdas WD, Pasquale LR; UK Biobank Eye and Vision Consortium, and for the International Glaucoma Genetics Consortium. Tran JH, et al. Among authors: ramdas wd. Transl Vis Sci Technol. 2023 Feb 1;12(2):20. doi: 10.1167/tvst.12.2.20. Transl Vis Sci Technol. 2023. PMID: 36786746 Free PMC article.
The Clinical Usefulness of a Glaucoma Polygenic Risk Score in 4 Population-Based European Ancestry Cohorts.
de Vries VA, Hanyuda A, Vergroesen JE, Do R, Friedman DS, Kraft P, Turman C, Luo YL, Tran JH, Liefers B, Wong SH, Lee RH, Zebardast N, Klaver CCW, Segrè AV, Pasquale LR, Wiggs JL, Kang JH, Ramdas WD. de Vries VA, et al. Among authors: ramdas wd. Ophthalmology. 2024 Aug 14:S0161-6420(24)00464-0. doi: 10.1016/j.ophtha.2024.08.005. Online ahead of print. Ophthalmology. 2024. PMID: 39128550 Free article.
Genes, pathways, and animal models in primary open-angle glaucoma.
Iglesias AI, Springelkamp H, Ramdas WD, Klaver CC, Willemsen R, van Duijn CM. Iglesias AI, et al. Among authors: ramdas wd. Eye (Lond). 2015 Oct;29(10):1285-98. doi: 10.1038/eye.2015.160. Epub 2015 Aug 28. Eye (Lond). 2015. PMID: 26315706 Free PMC article. Review.
78 results