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Pharmacologic C5-complement suppression reduces blood loss during on-pump cardiac surgery.
J Card Surg. 2005 Jan-Feb;20(1):35-41. doi: 10.1111/j.0886-0440.2005.200370.x.
J Card Surg. 2005.
PMID: 15673408
Clinical Trial.
Impact of pexelizumab, an anti-C5 complement antibody, on total mortality and adverse cardiovascular outcomes in cardiac surgical patients undergoing cardiopulmonary bypass.
Shernan SK, Fitch JC, Nussmeier NA, Chen JC, Rollins SA, Mojcik CF, Malloy KJ, Todaro TG, Filloon T, Boyce SW, Gangahar DM, Goldberg M, Saidman LJ, Mangano DT; Pexelizumab Study Investigators.
Shernan SK, et al.
Ann Thorac Surg. 2004 Mar;77(3):942-9; discussion 949-50. doi: 10.1016/j.athoracsur.2003.08.054.
Ann Thorac Surg. 2004.
PMID: 14992903
Clinical Trial.
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