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Most nocturnal asthma symptoms occur outside of exacerbations and associate with morbidity.
Horner CC, Mauger D, Strunk RC, Graber NJ, Lemanske RF Jr, Sorkness CA, Szefler SJ, Zeiger RS, Taussig LM, Bacharier LB; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Horner CC, et al. J Allergy Clin Immunol. 2011 Nov;128(5):977-82.e1-2. doi: 10.1016/j.jaci.2011.07.018. Epub 2011 Sep 8. J Allergy Clin Immunol. 2011. PMID: 21855126 Free PMC article. Clinical Trial.
Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthma.
Rabinovitch N, Graber NJ, Chinchilli VM, Sorkness CA, Zeiger RS, Strunk RC, Bacharier LB, Martinez FD, Szefler SJ; Childhood Asthma Research and Education Network of the National Heart, Lung, and Blood Institute. Rabinovitch N, et al. J Allergy Clin Immunol. 2010 Sep;126(3):545-51.e1-4. doi: 10.1016/j.jaci.2010.07.008. J Allergy Clin Immunol. 2010. PMID: 20816189 Free PMC article. Clinical Trial.