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Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice.
Kline JM, Arriaga-Gomez E, Yangdon T, Boo B, Landry J, Saldías-Montivero M, Neamonitaki N, Mengistu H, Silverio S, Zacheis H, Pasha D, Martinov T, Fife BT, Chatterjea D. Kline JM, et al. Among authors: neamonitaki n. PLoS One. 2020 Oct 26;15(10):e0241218. doi: 10.1371/journal.pone.0241218. eCollection 2020. PLoS One. 2020. PMID: 33104726 Free PMC article.
Repeated Vaginal Exposures to the Common Cosmetic and Household Preservative Methylisothiazolinone Induce Persistent, Mast Cell-Dependent Genital Pain in ND4 Mice.
Arriaga-Gomez E, Kline J, Emanuel E, Neamonitaki N, Yangdon T, Zacheis H, Pasha D, Lim J, Bush S, Boo B, Mengistu H, Kinnamon R, Shields-Cutler R, Wattenberg E, Chatterjea D. Arriaga-Gomez E, et al. Among authors: neamonitaki n. Int J Mol Sci. 2019 Oct 28;20(21):5361. doi: 10.3390/ijms20215361. Int J Mol Sci. 2019. PMID: 31661848 Free PMC article.