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Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft models.
Nat Commun. 2024 May 31;15(1):4653. doi: 10.1038/s41467-024-47547-3.
Nat Commun. 2024.
PMID: 38821942
Free PMC article.
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling.
Hobor S, Al Bakir M, Hiley CT, Skrzypski M, Frankell AM, Bakker B, Watkins TBK, Markovets A, Dry JR, Brown AP, van der Aart J, van den Bos H, Spierings D, Oukrif D, Novelli M, Chakrabarti T, Rabinowitz AH, Ait Hassou L, Litière S, Kerr DL, Tan L, Kelly G, Moore DA, Renshaw MJ, Venkatesan S, Hill W, Huebner A, Martínez-Ruiz C, Black JRM, Wu W, Angelova M, McGranahan N, Downward J, Chmielecki J, Barrett C, Litchfield K, Chew SK, Blakely CM, de Bruin EC, Foijer F, Vousden KH, Bivona TG; TRACERx consortium; Hynds RE, Kanu N, Zaccaria S, Grönroos E, Swanton C.
Hobor S, et al.
Nat Commun. 2024 Jun 13;15(1):4871. doi: 10.1038/s41467-024-47606-9.
Nat Commun. 2024.
PMID: 38871738
Free PMC article.
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MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Puttick C, Jones TP, Leung MM, Galvez-Cancino F, Liu J, Varas-Godoy M, Rowan A, Pich O, Martinez-Ruiz C, Bentham R, Dijkstra KK, Black JRM, Rosenthal R, Kanu N, Litchfield K, Salgado R, Moore DA, Van Loo P, Jamal-Hanjani M, Quezada SA; TRACERx Consortium; Swanton C, McGranahan N.
Puttick C, et al.
Nat Genet. 2024 Oct 2. doi: 10.1038/s41588-024-01883-8. Online ahead of print.
Nat Genet. 2024.
PMID: 39358601
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