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CD25-Treg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.
Solomon I, Amann M, Goubier A, Arce Vargas F, Zervas D, Qing C, Henry JY, Ghorani E, Akarca AU, Marafioti T, Śledzińska A, Werner Sunderland M, Franz Demane D, Clancy JR, Georgiou A, Salimu J, Merchiers P, Brown MA, Flury R, Eckmann J, Murgia C, Sam J, Jacobsen B, Marrer-Berger E, Boetsch C, Belli S, Leibrock L, Benz J, Koll H, Sutmuller R, Peggs KS, Quezada SA. Solomon I, et al. Among authors: koll h. Nat Cancer. 2020 Dec;1(12):1153-1166. doi: 10.1038/s43018-020-00133-0. Epub 2020 Nov 9. Nat Cancer. 2020. PMID: 33644766 Free PMC article.
Optimizing Early Clinical Investigations in Cancer Immunotherapy: The Translational Journey of RG6292, a Novel, Selective Treg-Depleting Antibody.
Belli S, Amann M, Hutchinson L, Pousse L, Abdolzade-Bavil A, Justies N, Jacobsen B, Ploix C, Tselempi E, Tosevski V, Koll H, Schnetzler G, Boetsch C, Marrer-Berger E. Belli S, et al. Among authors: koll h. Clin Pharmacol Ther. 2024 Sep;116(3):834-846. doi: 10.1002/cpt.3303. Epub 2024 May 20. Clin Pharmacol Ther. 2024. PMID: 38769868
Crystal structures of active SRC kinase domain complexes.
Breitenlechner CB, Kairies NA, Honold K, Scheiblich S, Koll H, Greiter E, Koch S, Schäfer W, Huber R, Engh RA. Breitenlechner CB, et al. Among authors: koll h. J Mol Biol. 2005 Oct 21;353(2):222-31. doi: 10.1016/j.jmb.2005.08.023. J Mol Biol. 2005. PMID: 16168436
22 results