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Year Number of Results
1959 1
1978 1
1979 2
1983 1
1986 3
1987 1
1989 1
1990 1
1991 2
1992 1
1993 3
1994 1
1995 2
1996 1
1997 1
1998 1
1999 2
2000 1
2001 4
2002 2
2004 3
2005 3
2006 5
2007 5
2008 2
2010 4
2011 9
2012 8
2013 5
2014 6
2015 13
2016 14
2017 8
2018 7
2019 16
2020 18
2021 20
2022 29
2023 30
2024 32
2025 3

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250 results

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Page 1
Macromolecular modeling and design in Rosetta: recent methods and frameworks.
Leman JK, Weitzner BD, Lewis SM, Adolf-Bryfogle J, Alam N, Alford RF, Aprahamian M, Baker D, Barlow KA, Barth P, Basanta B, Bender BJ, Blacklock K, Bonet J, Boyken SE, Bradley P, Bystroff C, Conway P, Cooper S, Correia BE, Coventry B, Das R, De Jong RM, DiMaio F, Dsilva L, Dunbrack R, Ford AS, Frenz B, Fu DY, Geniesse C, Goldschmidt L, Gowthaman R, Gray JJ, Gront D, Guffy S, Horowitz S, Huang PS, Huber T, Jacobs TM, Jeliazkov JR, Johnson DK, Kappel K, Karanicolas J, Khakzad H, Khar KR, Khare SD, Khatib F, Khramushin A, King IC, Kleffner R, Koepnick B, Kortemme T, Kuenze G, Kuhlman B, Kuroda D, Labonte JW, Lai JK, Lapidoth G, Leaver-Fay A, Lindert S, Linsky T, London N, Lubin JH, Lyskov S, Maguire J, Malmström L, Marcos E, Marcu O, Marze NA, Meiler J, Moretti R, Mulligan VK, Nerli S, Norn C, Ó'Conchúir S, Ollikainen N, Ovchinnikov S, Pacella MS, Pan X, Park H, Pavlovicz RE, Pethe M, Pierce BG, Pilla KB, Raveh B, Renfrew PD, Burman SSR, Rubenstein A, Sauer MF, Scheck A, Schief W, Schueler-Furman O, Sedan Y, Sevy AM, Sgourakis NG, Shi L, Siegel JB, Silva DA, Smith S, Song Y, Stein A, Szegedy M, Teets FD, Thyme SB, Wang RY, Watkins A, Zimmerman L, Bonneau R. Leman JK, et al. Among authors: huang ps. Nat Methods. 2020 Jul;17(7):665-680. doi: 10.1038/s41592-020-0848-2. Epub 2020 Jun 1. Nat Methods. 2020. PMID: 32483333 Free PMC article. Review.
Design of a hyperstable 60-subunit protein dodecahedron. [corrected].
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Hsia Y, et al. Among authors: huang ps. Nature. 2016 Jul 7;535(7610):136-9. doi: 10.1038/nature18010. Epub 2016 Jun 15. Nature. 2016. PMID: 27309817 Free PMC article.
Rational HIV immunogen design to target specific germline B cell receptors.
Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, Stamatatos L, Nemazee D, Wilson IA, Schief WR. Jardine J, et al. Among authors: huang ps. Science. 2013 May 10;340(6133):711-6. doi: 10.1126/science.1234150. Epub 2013 Mar 28. Science. 2013. PMID: 23539181 Free PMC article.
A general platform for targeting MHC-II antigens via a single loop.
Du H, Liu J, Jude KM, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Mobedi A, Parekh U, Sperberg RAP, Julien JP, Mellins ED, Garcia KC, Huang PS. Du H, et al. Among authors: huang ps. bioRxiv [Preprint]. 2024 Jan 30:2024.01.26.577489. doi: 10.1101/2024.01.26.577489. bioRxiv. 2024. PMID: 38352315 Free PMC article. Preprint.
Interleukin-2 superkines by computational design.
Ren J, Chu AE, Jude KM, Picton LK, Kare AJ, Su L, Montano Romero A, Huang PS, Garcia KC. Ren J, et al. Among authors: huang ps. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2117401119. doi: 10.1073/pnas.2117401119. Epub 2022 Mar 16. Proc Natl Acad Sci U S A. 2022. PMID: 35294290 Free PMC article.
Structure-based protein design with deep learning.
Ovchinnikov S, Huang PS. Ovchinnikov S, et al. Among authors: huang ps. Curr Opin Chem Biol. 2021 Dec;65:136-144. doi: 10.1016/j.cbpa.2021.08.004. Epub 2021 Sep 20. Curr Opin Chem Biol. 2021. PMID: 34547592 Free PMC article. Review.
Fully synthetic platform to rapidly generate tetravalent bispecific nanobody-based immunoglobulins.
Misson Mindrebo L, Liu H, Ozorowski G, Tran Q, Woehl J, Khalek I, Smith JM, Barman S, Zhao F, Keating C, Limbo O, Verma M, Liu J, Stanfield RL, Zhu X, Turner HL, Sok D, Huang PS, Burton DR, Ward AB, Wilson IA, Jardine JG. Misson Mindrebo L, et al. Among authors: huang ps. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2216612120. doi: 10.1073/pnas.2216612120. Epub 2023 Jun 5. Proc Natl Acad Sci U S A. 2023. PMID: 37276407 Free PMC article.
Sparks of function by de novo protein design.
Chu AE, Lu T, Huang PS. Chu AE, et al. Among authors: huang ps. Nat Biotechnol. 2024 Feb;42(2):203-215. doi: 10.1038/s41587-024-02133-2. Epub 2024 Feb 15. Nat Biotechnol. 2024. PMID: 38361073 Free PMC article. Review.
Competition-level code generation with AlphaCode.
Li Y, Choi D, Chung J, Kushman N, Schrittwieser J, Leblond R, Eccles T, Keeling J, Gimeno F, Dal Lago A, Hubert T, Choy P, de Masson d'Autume C, Babuschkin I, Chen X, Huang PS, Welbl J, Gowal S, Cherepanov A, Molloy J, Mankowitz DJ, Sutherland Robson E, Kohli P, de Freitas N, Kavukcuoglu K, Vinyals O. Li Y, et al. Among authors: huang ps. Science. 2022 Dec 9;378(6624):1092-1097. doi: 10.1126/science.abq1158. Epub 2022 Dec 8. Science. 2022. PMID: 36480631
250 results