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48 results

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Page 1
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Golde TE, Petyuk VA, De Jager PL, Bennett DA, Wingo TS, Rangaraju S, Hajjar I, Shulman JM, Lah JJ, Levey AI, Seyfried NT. Johnson ECB, et al. Among authors: higginbotham la. Nat Med. 2020 May;26(5):769-780. doi: 10.1038/s41591-020-0815-6. Epub 2020 Apr 13. Nat Med. 2020. PMID: 32284590 Free PMC article.
Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial.
NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee; Wall M, McDermott MP, Kieburtz KD, Corbett JJ, Feldon SE, Friedman DI, Katz DM, Keltner JL, Schron EB, Kupersmith MJ. NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee, et al. JAMA. 2014 Apr 23-30;311(16):1641-51. doi: 10.1001/jama.2014.3312. JAMA. 2014. PMID: 24756514 Free PMC article. Clinical Trial.
Preventing T cell rejection of pig xenografts.
Higginbotham L, Ford ML, Newell KA, Adams AB. Higginbotham L, et al. Int J Surg. 2015 Nov;23(Pt B):285-290. doi: 10.1016/j.ijsu.2015.07.722. Epub 2015 Aug 22. Int J Surg. 2015. PMID: 26306770 Free article. Review.
Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Shantaraman A, et al. Among authors: higginbotham l. Mol Neurodegener. 2024 Aug 6;19(1):60. doi: 10.1186/s13024-024-00749-1. Mol Neurodegener. 2024. PMID: 39107789 Free PMC article.
CD28-Selective Inhibition Prolongs Non-Human Primate Kidney Transplant Survival.
Lovasik BP, Kim SC, Higginbotham L, Wakwe W, Mathews DV, Breeden C, Farris AB, Larsen CP, Ford ML, Nadler S, Adams AB. Lovasik BP, et al. Among authors: higginbotham l. bioRxiv [Preprint]. 2023 May 5:2023.05.03.539333. doi: 10.1101/2023.05.03.539333. bioRxiv. 2023. PMID: 37205571 Free PMC article. Preprint.
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment.
Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, Hajjar I, Fagan AM, Galasko D, Edland SD, Hanfelt J, Lah JJ, Weinshenker D. Levey AI, et al. Among authors: higginbotham l. Brain. 2022 Jun 30;145(6):1924-1938. doi: 10.1093/brain/awab452. Brain. 2022. PMID: 34919634 Free PMC article. Clinical Trial.
Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
Higginbotham L, Carter EK, Dammer EB, Haque RU, Johnson ECB, Duong DM, Yin L, De Jager PL, Bennett DA, Felsky D, Tio ES, Lah JJ, Levey AI, Seyfried NT. Higginbotham L, et al. Neurobiol Dis. 2023 Oct 1;186:106286. doi: 10.1016/j.nbd.2023.106286. Epub 2023 Sep 7. Neurobiol Dis. 2023. PMID: 37689213 Free PMC article.
Should responder analyses be conducted on continuous outcomes?
Abugov R, Clark J, Higginbotham L, Li F, Nie L, Reasner D, Rothmann M, Yuan X, Sharretts J. Abugov R, et al. Among authors: higginbotham l. Pharm Stat. 2023 Mar;22(2):312-327. doi: 10.1002/pst.2273. Epub 2022 Nov 23. Pharm Stat. 2023. PMID: 36418046
48 results