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Page 1
Discontinuation vs. continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial.
Ackland GL, Patel A, Abbott TEF, Begum S, Dias P, Crane DR, Somanath S, Middleditch A, Cleland S, Gutierrez Del Arroyo A, Brealey D, Pearse RM; Stopping Perioperative ACE-inhibitors or angiotensin-II receptor blockers (SPACE) trial investigators. Ackland GL, et al. Eur Heart J. 2024 Apr 1;45(13):1146-1155. doi: 10.1093/eurheartj/ehad716. Eur Heart J. 2024. PMID: 37935833 Free PMC article. Clinical Trial.
Preoperative assessment of the older patient.
Pang CL, Gooneratne M, Partridge JSL. Pang CL, et al. Among authors: gooneratne m. BJA Educ. 2021 Aug;21(8):314-320. doi: 10.1016/j.bjae.2021.03.005. Epub 2021 May 4. BJA Educ. 2021. PMID: 34306733 Free PMC article. Review. No abstract available.
Rapid response systems and the deteriorating patient.
Gooneratne M, Walker D. Gooneratne M, et al. Br J Hosp Med (Lond). 2017 Mar 2;78(3):124-125. doi: 10.12968/hmed.2017.78.3.124. Br J Hosp Med (Lond). 2017. PMID: 28277762 No abstract available.
Obstructive sleep apnoea and perioperative medicine: a growing concern.
Chambers T, Ruparelia P, Ellis G, Bishop T, Gooneratne M, Singh N. Chambers T, et al. Among authors: gooneratne m. Br J Hosp Med (Lond). 2022 Sep 2;83(9):1-9. doi: 10.12968/hmed.2022.0297. Epub 2022 Sep 28. Br J Hosp Med (Lond). 2022. PMID: 36193921 Free article. Review.
Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin-angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial.
Gutierrez Del Arroyo A, Patel A, Abbott TEF, Begum S, Dias P, Somanath S, Middleditch A, Cleland S, Brealey D, Pearse RM, Ackland GL; SPACE trial investigators. Gutierrez Del Arroyo A, et al. Br J Anaesth. 2024 May;132(5):857-866. doi: 10.1016/j.bja.2024.01.010. Epub 2024 Feb 9. Br J Anaesth. 2024. PMID: 38341283 Free PMC article. Clinical Trial.
Fluid Optimisation in Emergency Laparotomy (FLO-ELA) Trial: study protocol for a multi-centre randomised trial of cardiac output-guided fluid therapy compared to usual care in patients undergoing major emergency gastrointestinal surgery.
Edwards MR, Forbes G, Walker N, Morton DG, Mythen MG, Murray D, Anderson I, Mihaylova B, Thomson A, Taylor M, Hollyman M, Phillips R, Young K, Kahan BC, Pearse RM, Grocott MPW; FLO-ELA investigators. Edwards MR, et al. Trials. 2023 May 6;24(1):313. doi: 10.1186/s13063-023-07275-3. Trials. 2023. PMID: 37149623 Free PMC article.
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