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Page 1
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N, Cabrera CP, Karaman I, Ng FL, Evangelou M, Witkowska K, Tzanis E, Hellwege JN, Giri A, Velez Edwards DR, Sun YV, Cho K, Gaziano JM, Wilson PWF, Tsao PS, Kovesdy CP, Esko T, Mägi R, Milani L, Almgren P, Boutin T, Debette S, Ding J, Giulianini F, Holliday EG, Jackson AU, Li-Gao R, Lin WY, Luan J, Mangino M, Oldmeadow C, Prins BP, Qian Y, Sargurupremraj M, Shah N, Surendran P, Thériault S, Verweij N, Willems SM, Zhao JH, Amouyel P, Connell J, de Mutsert R, Doney ASF, Farrall M, Menni C, Morris AD, Noordam R, Paré G, Poulter NR, Shields DC, Stanton A, Thom S, Abecasis G, Amin N, Arking DE, Ayers KL, Barbieri CM, Batini C, Bis JC, Blake T, Bochud M, Boehnke M, Boerwinkle E, Boomsma DI, Bottinger EP, Braund PS, Brumat M, Campbell A, Campbell H, Chakravarti A, Chambers JC, Chauhan G, Ciullo M, Cocca M, Collins F, Cordell HJ, Davies G, de Borst MH, de Geus EJ, Deary IJ, Deelen J, Del Greco M F, Demirkale CY, Dörr M, Ehret GB, Elosua R, Enroth S, Erzurumluoglu AM, Ferreira T, Frånberg M, Franco OH, Gandin I, Gasparini P, Giedraitis V, Gieger C, Girotto G, Goel A, Gow AJ, Gudnason V, Guo X, Gyll… See abstract for full author list ➔ Evangelou E, et al. Among authors: demirkale cy. Nat Genet. 2018 Oct;50(10):1412-1425. doi: 10.1038/s41588-018-0205-x. Epub 2018 Sep 17. Nat Genet. 2018. PMID: 30224653 Free PMC article.
Inappropriate empirical antibiotic therapy for bloodstream infections based on discordant in-vitro susceptibilities: a retrospective cohort analysis of prevalence, predictors, and mortality risk in US hospitals.
Kadri SS, Lai YL, Warner S, Strich JR, Babiker A, Ricotta EE, Demirkale CY, Dekker JP, Palmore TN, Rhee C, Klompas M, Hooper DC, Powers JH 3rd, Srinivasan A, Danner RL, Adjemian J; forming the National Insititutes of Health Antimicrobial Resistance Outcomes Research Initiative (NIH-ARORI). Kadri SS, et al. Among authors: demirkale cy. Lancet Infect Dis. 2021 Feb;21(2):241-251. doi: 10.1016/S1473-3099(20)30477-1. Epub 2020 Sep 8. Lancet Infect Dis. 2021. PMID: 32916100 Free PMC article.
Anti-PD-L1 therapy altered inflammation but not survival in a lethal murine hepatitis virus-1 pneumonia model.
Curran CS, Cui X, Li Y, Jeakle M, Sun J, Demirkale CY, Minkove S, Hoffmann V, Dhamapurkar R, Chumbris S, Bolyard C, Iheanacho A, Eichacker PQ, Torabi-Parizi P. Curran CS, et al. Among authors: demirkale cy. Front Immunol. 2024 Jan 8;14:1308358. doi: 10.3389/fimmu.2023.1308358. eCollection 2023. Front Immunol. 2024. PMID: 38259435 Free PMC article.
Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss.
Dougherty EJ, Chen LY, Awad KS, Ferreyra GA, Demirkale CY, Keshavarz A, Gairhe S, Johnston KA, Hicks ME, Sandler AB, Curran CS, Krack JM, Ding Y, Suffredini AF, Solomon MA, Elinoff JM, Danner RL. Dougherty EJ, et al. Among authors: demirkale cy. Am J Physiol Lung Cell Mol Physiol. 2023 Jun 1;324(6):L783-L798. doi: 10.1152/ajplung.00171.2022. Epub 2023 Apr 11. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37039367 Free PMC article.
Type I interferon activation and endothelial dysfunction in caveolin-1 insufficiency-associated pulmonary arterial hypertension.
Gairhe S, Awad KS, Dougherty EJ, Ferreyra GA, Wang S, Yu ZX, Takeda K, Demirkale CY, Torabi-Parizi P, Austin ED, Elinoff JM, Danner RL. Gairhe S, et al. Among authors: demirkale cy. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2010206118. doi: 10.1073/pnas.2010206118. Proc Natl Acad Sci U S A. 2021. PMID: 33836561 Free PMC article.
Plasma Cell-Free DNA Predicts Survival and Maps Specific Sources of Injury in Pulmonary Arterial Hypertension.
Brusca SB, Elinoff JM, Zou Y, Jang MK, Kong H, Demirkale CY, Sun J, Seifuddin F, Pirooznia M, Valantine HA, Tanba C, Chaturvedi A, Graninger GM, Harper B, Chen LY, Cole J, Kanwar M, Benza RL, Preston IR, Agbor-Enoh S, Solomon MA. Brusca SB, et al. Among authors: demirkale cy. Circulation. 2022 Oct 4;146(14):1033-1045. doi: 10.1161/CIRCULATIONAHA.121.056719. Epub 2022 Aug 25. Circulation. 2022. PMID: 36004627 Free PMC article.
39 results