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Upregulation of PD-L1 in Senescence and Aging.
Onorati A, Havas AP, Lin B, Rajagopal J, Sen P, Adams PD, Dou Z. Onorati A, et al. Mol Cell Biol. 2022 Oct 20;42(10):e0017122. doi: 10.1128/mcb.00171-22. Epub 2022 Sep 26. Mol Cell Biol. 2022. PMID: 36154662 Free PMC article.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116496 Free PMC article.
Loss of H3K9 trimethylation leads to premature aging.
Mrabti C, Yang N, Desdín-Micó G, Alonso-Calleja A, Vílchez-Acosta A, Pico S, Parras A, Piao Y, Schoenfeldt L, Luo S, Haghani A, Brooke R, Del Carmen Maza M, Branchina C, Maroun CY, von Meyenn F, Naveiras O, Horvath S, Sen P, Ocampo A. Mrabti C, et al. bioRxiv [Preprint]. 2024 Jul 24:2024.07.24.604929. doi: 10.1101/2024.07.24.604929. bioRxiv. 2024. PMID: 39091811 Free PMC article. Preprint.
Linking Aging to Cancer: The Role of Chromatin Biology.
Corveleyn L, Sen P, Adams P, Sidoli S. Corveleyn L, et al. J Gerontol A Biol Sci Med Sci. 2024 Jul 1;79(7):glae133. doi: 10.1093/gerona/glae133. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38761362 Review.
The eroding chromatin landscape of aging stem cells.
Shi C, Wang L, Sen P. Shi C, et al. Transl Med Aging. 2020;4:121-131. doi: 10.1016/j.tma.2020.08.002. Epub 2020 Aug 17. Transl Med Aging. 2020. PMID: 33024907 Free PMC article.
15 results