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2021 1
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Page 1
Gene editing therapeutics based on mRNA delivery.
Popovitz J, Sharma R, Hoshyar R, Soo Kim B, Murthy N, Lee K. Popovitz J, et al. Adv Drug Deliv Rev. 2023 Sep;200:115026. doi: 10.1016/j.addr.2023.115026. Epub 2023 Jul 27. Adv Drug Deliv Rev. 2023. PMID: 37516409 Review.
Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy.
Tang Y, Chaillon A, Gianella S, Wong LM, Li D, Simermeyer TL, Porrachia M, Ignacio C, Woodworth B, Zhong D, Du J, de la Parra Polina E, Kirchherr J, Allard B, Clohosey ML, Moeser M, Sondgeroth AL, Whitehill GD, Singh V, Dashti A, Smith DM, Eron JJ, Bar KJ, Chahroudi A, Joseph SB, Archin NM, Margolis DM, Jiang G. Tang Y, et al. J Clin Invest. 2023 Jun 15;133(12):e167417. doi: 10.1172/JCI167417. J Clin Invest. 2023. PMID: 37317962 Free PMC article.
Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection.
Ahuja SK, Manoharan MS, Lee GC, McKinnon LR, Meunier JA, Steri M, Harper N, Fiorillo E, Smith AM, Restrepo MI, Branum AP, Bottomley MJ, Orrù V, Jimenez F, Carrillo A, Pandranki L, Winter CA, Winter LA, Gaitan AA, Moreira AG, Walter EA, Silvestri G, King CL, Zheng YT, Zheng HY, Kimani J, Blake Ball T, Plummer FA, Fowke KR, Harden PN, Wood KJ, Ferris MT, Lund JM, Heise MT, Garrett N, Canady KR, Abdool Karim SS, Little SJ, Gianella S, Smith DM, Letendre S, Richman DD, Cucca F, Trinh H, Sanchez-Reilly S, Hecht JM, Cadena Zuluaga JA, Anzueto A, Pugh JA; South Texas Veterans Health Care System COVID-19 team; Agan BK, Root-Bernstein R, Clark RA, Okulicz JF, He W. Ahuja SK, et al. Nat Commun. 2023 Jun 13;14(1):3286. doi: 10.1038/s41467-023-38238-6. Nat Commun. 2023. PMID: 37311745 Free PMC article.
RNA conformational propensities determine cellular activity.
Ken ML, Roy R, Geng A, Ganser LR, Manghrani A, Cullen BR, Schulze-Gahmen U, Herschlag D, Al-Hashimi HM. Ken ML, et al. Nature. 2023 May;617(7962):835-841. doi: 10.1038/s41586-023-06080-x. Epub 2023 May 17. Nature. 2023. PMID: 37198487 Free PMC article.
HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing.
Lyons DE, Kumar P, Roan NR, Defechereux PA, Feschotte C, Lange UC, Murthy N, Sameshima P, Verdin E, Ake JA, Parsons MS, Nath A, Gianella S, Smith DM, Kallas EG, Villa TJ, Strange R, Mwesigwa B, Furler O'Brien RL, Nixon DF, Ndhlovu LC, Valente ST, Ott M. Lyons DE, et al. Viruses. 2023 Oct 28;15(11):2171. doi: 10.3390/v15112171. Viruses. 2023. PMID: 38005849 Free PMC article.
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data.
Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, Chawla DG, Soares-Schanoski A, Spurbeck RR, Ndhlovu LC, Sebra R, Kleinstein SH, Letizia AG, Ramos I, Fowler VG Jr, Woods CW, Zaslavsky E, Troyanskaya OG, Sealfon SC. Chen X, et al. Nat Comput Sci. 2023 Jul;3(7):644-657. doi: 10.1038/s43588-023-00476-5. Epub 2023 Jul 25. Nat Comput Sci. 2023. PMID: 37974651 Free PMC article.
63 results