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2022 10
2023 25
2024 19
2025 1

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Page 1
Birth of protein folds and functions in the virome.
Nomburg J, Doherty EE, Price N, Bellieny-Rabelo D, Zhu YK, Doudna JA. Nomburg J, et al. Nature. 2024 Sep;633(8030):710-717. doi: 10.1038/s41586-024-07809-y. Epub 2024 Aug 26. Nature. 2024. PMID: 39187718 Free PMC article.
IFITM proteins assist cellular uptake of diverse linked chemotypes.
Lou K, Wassarman DR, Yang T, Paung Y, Zhang Z, O'Loughlin TA, Moore MK, Egan RK, Greninger P, Benes CH, Seeliger MA, Taunton J, Gilbert LA, Shokat KM. Lou K, et al. Science. 2022 Dec 9;378(6624):1097-1104. doi: 10.1126/science.abl5829. Epub 2022 Dec 8. Science. 2022. PMID: 36480603 Free PMC article.
SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, Stevenson E, Rojc A, Ragazzini R, Whelan MVX, Furnon W, De Lorenzo G, Cowton V, Syed AM, Ciling A, Deutsch N, Pirak D, Dowgier G, Mesner D, Turner JL, McGovern BL, Rodriguez ML, Leiva-Rebollo R, Dunham AS, Zhong X, Eckhardt M, Fossati A, Liotta NF, Kehrer T, Cupic A, Rutkowska M, Mena I, Aslam S, Hoffert A, Foussard H, Olwal CO, Huang W, Zwaka T, Pham J, Lyons M, Donohue L, Griffin A, Nugent R, Holden K, Deans R, Aviles P, Lopez-Martin JA, Jimeno JM, Obernier K, Fabius JM, Soucheray M, Hüttenhain R, Jungreis I, Kellis M, Echeverria I, Verba K, Bonfanti P, Beltrao P, Sharan R, Doudna JA, Martinez-Sobrido L, Patel AH, Palmarini M, Miorin L, White K, Swaney DL, Garcia-Sastre A, Jolly C, Zuliani-Alvarez L, Towers GJ, Krogan NJ. Bouhaddou M, et al. Cell. 2023 Oct 12;186(21):4597-4614.e26. doi: 10.1016/j.cell.2023.08.026. Epub 2023 Sep 21. Cell. 2023. PMID: 37738970 Free PMC article.
Altered RSV Epidemiology and Genetic Diversity Following the COVID-19 Pandemic.
Hultquist J, Rios-Guzman E, Simons L, Dean T, Agnes F, Pawlowski A, Alisoltanidehkordi A, Nam H, Ison M, Ozer E, Lorenzo-Redondo R. Hultquist J, et al. Res Sq [Preprint]. 2023 Dec 15:rs.3.rs-3712859. doi: 10.21203/rs.3.rs-3712859/v1. Res Sq. 2023. Update in: Nat Commun. 2024 Apr 20;15(1):3374. doi: 10.1038/s41467-024-47757-9 PMID: 38168164 Free PMC article. Updated. Preprint.
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9.
Eggers AR, Chen K, Soczek KM, Tuck OT, Doherty EE, Xu B, Trinidad MI, Thornton BW, Yoon PH, Doudna JA. Eggers AR, et al. Cell. 2024 Jun 20;187(13):3249-3261.e14. doi: 10.1016/j.cell.2024.04.031. Epub 2024 May 22. Cell. 2024. PMID: 38781968 Free PMC article.
Preparing for the next pandemic.
Shoichet BK, Craik CS. Shoichet BK, et al. Science. 2023 Nov 10;382(6671):649-650. doi: 10.1126/science.adk5868. Epub 2023 Nov 9. Science. 2023. PMID: 37943911 Free PMC article.
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.
Taha TY, Suryawanshi RK, Chen IP, Correy GJ, McCavitt-Malvido M, O'Leary PC, Jogalekar MP, Diolaiti ME, Kimmerly GR, Tsou CL, Gascon R, Montano M, Martinez-Sobrido L, Krogan NJ, Ashworth A, Fraser JS, Ott M. Taha TY, et al. PLoS Pathog. 2023 Aug 31;19(8):e1011614. doi: 10.1371/journal.ppat.1011614. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37651466 Free PMC article.
Neuronal DNA repair reveals strategies to influence CRISPR editing outcomes.
Ramadoss GN, Namaganda SJ, Hamilton JR, Sharma R, Chow KG, Macklin BL, Sun M, Liu JC, Fellmann C, Watry HL, Jin J, Perez BS, Sandoval Espinoza CR, Matia MP, Lu SH, Judge LM, Nussenzweig A, Adamson B, Murthy N, Doudna JA, Kampmann M, Conklin BR. Ramadoss GN, et al. bioRxiv [Preprint]. 2024 Jun 26:2024.06.25.600517. doi: 10.1101/2024.06.25.600517. bioRxiv. 2024. PMID: 38979269 Free PMC article. Preprint.
54 results