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Page 1
The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable.
Benod C, Villagomez R, Filgueira CS, Hwang PK, Leonard PG, Poncet-Montange G, Rajagopalan S, Fletterick RJ, Gustafsson JÅ, Webb P. Benod C, et al. PLoS One. 2014 Jun 17;9(6):e99440. doi: 10.1371/journal.pone.0099440. eCollection 2014. PLoS One. 2014. PMID: 24936658 Free PMC article.
Structure-based discovery of antagonists of nuclear receptor LRH-1.
Benod C, Carlsson J, Uthayaruban R, Hwang P, Irwin JJ, Doak AK, Shoichet BK, Sablin EP, Fletterick RJ. Benod C, et al. J Biol Chem. 2013 Jul 5;288(27):19830-44. doi: 10.1074/jbc.M112.411686. Epub 2013 May 10. J Biol Chem. 2013. PMID: 23667258 Free PMC article.
Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.
Spencer CI, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomoda K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setälä K, Makielski JC, January CT, Healy KE, Kamp TJ, Yamanaka S, Conklin BR. Spencer CI, et al. Stem Cell Reports. 2014 Aug 12;3(2):269-81. doi: 10.1016/j.stemcr.2014.06.003. Epub 2014 Jul 4. Stem Cell Reports. 2014. PMID: 25254341 Free PMC article.
18 results