U01 AI074564/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	2
2009	3
2010	4
2011	11
2012	5
2013	6
2014	3
2017	1
2024	0

1

Quelling the storm: utilization of sphingosine-1-phosphate receptor signaling to ameliorate influenza virus-induced cytokine storm.

Walsh KB, Teijaro JR, Rosen H, Oldstone MB. Walsh KB, et al. Immunol Res. 2011 Oct;51(1):15-25. doi: 10.1007/s12026-011-8240-z. Immunol Res. 2011. PMID: 21901448 Review.

2

Lessons learned and concepts formed from study of the pathogenesis of the two negative-strand viruses lymphocytic choriomeningitis and influenza.

Oldstone MB. Oldstone MB. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4180-3. doi: 10.1073/pnas.1222025110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341590 Free PMC article. Review.

3

Cytokine storm plays a direct role in the morbidity and mortality from influenza virus infection and is chemically treatable with a single sphingosine-1-phosphate agonist molecule.

Oldstone MB, Rosen H. Oldstone MB, et al. Curr Top Microbiol Immunol. 2014;378:129-47. doi: 10.1007/978-3-319-05879-5_6. Curr Top Microbiol Immunol. 2014. PMID: 24728596 Free PMC article. Review.

4

The pathogenesis of influenza virus infections: the contributions of virus and host factors.

Fukuyama S, Kawaoka Y. Fukuyama S, et al. Curr Opin Immunol. 2011 Aug;23(4):481-6. doi: 10.1016/j.coi.2011.07.016. Epub 2011 Aug 11. Curr Opin Immunol. 2011. PMID: 21840185 Free PMC article. Review.

5

Dissecting influenza virus pathogenesis uncovers a novel chemical approach to combat the infection.

Oldstone MB, Teijaro JR, Walsh KB, Rosen H. Oldstone MB, et al. Virology. 2013 Jan 5;435(1):92-101. doi: 10.1016/j.virol.2012.09.039. Virology. 2013. PMID: 23217619 Free PMC article. Review.

6

Chemical modulators of sphingosine-1-phosphate receptors as barrier-oriented therapeutic molecules.

Marsolais D, Rosen H. Marsolais D, et al. Nat Rev Drug Discov. 2009 Apr;8(4):297-307. doi: 10.1038/nrd2356. Epub 2009 Mar 20. Nat Rev Drug Discov. 2009. PMID: 19300460 Free PMC article. Review.

7

Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist.

Guerrero M, Poddutoori R, Urbano M, Peng X, Spicer TP, Chase PS, Hodder PS, Schaeffer MT, Brown S, Rosen H, Roberts E. Guerrero M, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6346-9. doi: 10.1016/j.bmcl.2013.09.075. Epub 2013 Oct 1. Bioorg Med Chem Lett. 2013. PMID: 24135724 Free PMC article.

8

Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists.

Guerrero M, Urbano M, Zhao J, Crisp M, Chase P, Hodder P, Schaeffer MT, Brown S, Rosen H, Roberts E. Guerrero M, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42. doi: 10.1016/j.bmcl.2011.10.096. Epub 2011 Nov 4. Bioorg Med Chem Lett. 2012. PMID: 22119461 Free PMC article.

9

Influenza NS1 directly modulates Hedgehog signaling during infection.

Smelkinson MG, Guichard A, Teijaro JR, Malur M, Loureiro ME, Jain P, Ganesan S, Zúñiga EI, Krug RM, Oldstone MB, Bier E. Smelkinson MG, et al. PLoS Pathog. 2017 Aug 24;13(8):e1006588. doi: 10.1371/journal.ppat.1006588. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28837667 Free PMC article.

10

Crystal structure of a lipid G protein-coupled receptor.

Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Hanson MA, et al. Science. 2012 Feb 17;335(6070):851-5. doi: 10.1126/science.1215904. Science. 2012. PMID: 22344443 Free PMC article.

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