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Alzheimer's disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression.
Ropri AS, Lam TG, Kalia V, Buchanan HM, Bartosch AMW, Youth EHH, Xiao H, Ross SK, Jain A, Chakrabarty JK, Kang MS, Boyett D, Spinazzi EF, Iodice G, McGovern RA, Honig LS, Brown LM, Miller GW, McKhann GM, Teich AF. Ropri AS, et al. Alzheimers Dement. 2024 Oct;20(10):7090-7103. doi: 10.1002/alz.14194. Epub 2024 Aug 27. Alzheimers Dement. 2024. PMID: 39192661 Free PMC article.
Xenografted human iPSC-derived neurons with the familial Alzheimer's disease APPV717I mutation reveal dysregulated transcriptome signatures linked to synaptic function and implicate LINGO2 as a disease signaling mediator.
Qu W, Lam M, McInvale JJ, Mares JA, Kwon S, Humala N, Mahajan A, Nguyen T, Jakubiak KA, Mun JY, Tedesco TG, Al-Dalahmah O, Hussaini SA, Sproul AA, Siegelin MD, De Jager PL, Canoll P, Menon V, Hargus G. Qu W, et al. Acta Neuropathol. 2024 Jun 25;147(1):107. doi: 10.1007/s00401-024-02755-5. Acta Neuropathol. 2024. PMID: 38918213 Free PMC article.
Molsidomine provides neuroprotection against vincristine-induced peripheral neurotoxicity through soluble guanylyl cyclase activation.
Utkina-Sosunova I, Chiorazzi A, de Planell-Saguer M, Li H, Meregalli C, Pozzi E, Carozzi VA, Canta A, Monza L, Alberti P, Fumagalli G, Karan C, Moayedi Y, Przedborski S, Cavaletti G, Lotti F. Utkina-Sosunova I, et al. Sci Rep. 2024 Aug 20;14(1):19341. doi: 10.1038/s41598-024-70294-w. Sci Rep. 2024. PMID: 39164364 Free PMC article.
18 results