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Psoriasis genetics: breaking the barrier.
Roberson ED, Bowcock AM. Roberson ED, et al. Trends Genet. 2010 Sep;26(9):415-23. doi: 10.1016/j.tig.2010.06.006. Epub 2010 Aug 6. Trends Genet. 2010. PMID: 20692714 Free PMC article. Review.
PSORS2 is due to mutations in CARD14.
Jordan CT, Cao L, Roberson ED, Pierson KC, Yang CF, Joyce CE, Ryan C, Duan S, Helms CA, Liu Y, Chen Y, McBride AA, Hwu WL, Wu JY, Chen YT, Menter A, Goldbach-Mansky R, Lowes MA, Bowcock AM. Jordan CT, et al. Am J Hum Genet. 2012 May 4;90(5):784-95. doi: 10.1016/j.ajhg.2012.03.012. Epub 2012 Apr 19. Am J Hum Genet. 2012. PMID: 22521418 Free PMC article.
A subset of methylated CpG sites differentiate psoriatic from normal skin.
Roberson ED, Liu Y, Ryan C, Joyce CE, Duan S, Cao L, Martin A, Liao W, Menter A, Bowcock AM. Roberson ED, et al. J Invest Dermatol. 2012 Mar;132(3 Pt 1):583-92. doi: 10.1038/jid.2011.348. Epub 2011 Nov 10. J Invest Dermatol. 2012. PMID: 22071477 Free PMC article.
Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.
Jordan CT, Cao L, Roberson ED, Duan S, Helms CA, Nair RP, Duffin KC, Stuart PE, Goldgar D, Hayashi G, Olfson EH, Feng BJ, Pullinger CR, Kane JP, Wise CA, Goldbach-Mansky R, Lowes MA, Peddle L, Chandran V, Liao W, Rahman P, Krueger GG, Gladman D, Elder JT, Menter A, Bowcock AM. Jordan CT, et al. Am J Hum Genet. 2012 May 4;90(5):796-808. doi: 10.1016/j.ajhg.2012.03.013. Epub 2012 Apr 19. Am J Hum Genet. 2012. PMID: 22521419 Free PMC article.