T32 GM152349/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2024	21
2025	3

1

Pharmacological restoration of GTP hydrolysis by mutant RAS.

Cuevas-Navarro A, Pourfarjam Y, Hu F, Rodriguez DJ, Vides A, Sang B, Fan S, Goldgur Y, de Stanchina E, Lito P. Cuevas-Navarro A, et al. Nature. 2025 Jan;637(8044):224-229. doi: 10.1038/s41586-024-08283-2. Epub 2024 Oct 30. Nature. 2025. PMID: 39476862 Free PMC article.

2

Precursor central memory versus effector cell fate and naïve CD4+ T cell heterogeneity.

Deep D, Gudjonson H, Brown CC, Rose SA, Sharma R, Paucar Iza YA, Hong S, Hemmers S, Schizas M, Wang ZM, Chen Y, Wesemann DR, Pascual V, Pe'er D, Rudensky AY. Deep D, et al. J Exp Med. 2024 Oct 7;221(10):e20231193. doi: 10.1084/jem.20231193. Epub 2024 Sep 25. J Exp Med. 2024. PMID: 39321257 Free PMC article.

3

A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer.

Singhal A, Styers HC, Rub J, Li Z, Torborg SR, Kim JY, Grbovic-Huezo O, Feng H, Tarcan ZC, Sahin Ozkan H, Hallin J, Basturk O, Yaeger R, Christensen JG, Betel D, Yan Y, Chio IIC, de Stanchina E, Tammela T. Singhal A, et al. Cancer Discov. 2024 Nov 1;14(11):2122-2134. doi: 10.1158/2159-8290.CD-24-0740. Cancer Discov. 2024. PMID: 38975873

4

Automatic ploidy prediction and quality assessment of human blastocysts using time-lapse imaging.

Rajendran S, Brendel M, Barnes J, Zhan Q, Malmsten JE, Zisimopoulos P, Sigaras A, Ofori-Atta K, Meseguer M, Miller KA, Hoffman D, Rosenwaks Z, Elemento O, Zaninovic N, Hajirasouliha I. Rajendran S, et al. Nat Commun. 2024 Sep 5;15(1):7756. doi: 10.1038/s41467-024-51823-7. Nat Commun. 2024. PMID: 39237547 Free PMC article.

5

Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer.

McIntyre CA, Grimont A, Park J, Meng Y, Sisso WJ, Seier K, Jang GH, Walch H, Aveson VG, Falvo DJ, Fall WB, Chan CW, Wenger A, Ecker BL, Pulvirenti A, Gelfer R, Zafra MP, Schultz N, Park W, O'Reilly EM, Houlihan SL, Alonso A, Hissong E, Church GM, Mason CE, Siolas D, Notta F, Gonen M, Dow LE, Jarnagin WR, Chandwani R. McIntyre CA, et al. Cancer Cell. 2024 Sep 9;42(9):1614-1629.e5. doi: 10.1016/j.ccell.2024.08.002. Epub 2024 Aug 29. Cancer Cell. 2024. PMID: 39214094

6

A bacterial TIR-based immune system senses viral capsids to initiate defense.

Roberts CG, Fishman CB, Banh DV, Marraffini LA. Roberts CG, et al. bioRxiv [Preprint]. 2024 Jul 29:2024.07.29.605636. doi: 10.1101/2024.07.29.605636. bioRxiv. 2024. PMID: 39131286 Free PMC article. Preprint.

7

Defining heritability, plasticity, and transition dynamics of cellular phenotypes in somatic evolution.

Schiffman JS, D'Avino AR, Prieto T, Pang Y, Fan Y, Rajagopalan S, Potenski C, Hara T, Suvà ML, Gawad C, Landau DA. Schiffman JS, et al. Nat Genet. 2024 Oct;56(10):2174-2184. doi: 10.1038/s41588-024-01920-6. Epub 2024 Sep 24. Nat Genet. 2024. PMID: 39317739

8

Nanomechanics of wild-type and mutant dimers of the inner-ear tip-link protein protocadherin 15.

Villasante CM, Deng X, Cohen JE, Hudspeth AJ. Villasante CM, et al. Proc Natl Acad Sci U S A. 2024 Oct;121(40):e2404829121. doi: 10.1073/pnas.2404829121. Epub 2024 Sep 19. Proc Natl Acad Sci U S A. 2024. PMID: 39298473 Free PMC article.

9

The chemokine Cxcl14 regulates interneuron differentiation in layer I of the somatosensory cortex.

Iannone AF, Akgül G, Zhang R, Wacks S, Hussein N, Macias CG, Donatelle A, Bauriedel JMJ, Wright C, Abramov D, Johnson MA, Govek EE, Burré J, Milner TA, De Marco García NV. Iannone AF, et al. Cell Rep. 2024 Aug 27;43(8):114531. doi: 10.1016/j.celrep.2024.114531. Epub 2024 Jul 25. Cell Rep. 2024. PMID: 39058591 Free PMC article.

10

Uncoupling of mTORC1 from E2F activity maintains DNA damage and senescence.

Daigh LH, Saha D, Rosenthal DL, Ferrick KR, Meyer T. Daigh LH, et al. Nat Commun. 2024 Oct 24;15(1):9181. doi: 10.1038/s41467-024-52820-6. Nat Commun. 2024. PMID: 39448567 Free PMC article.

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