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Molecular Glue Discovery: Current and Future Approaches.
Dewey JA, Delalande C, Azizi SA, Lu V, Antonopoulos D, Babnigg G. Dewey JA, et al. J Med Chem. 2023 Jul 27;66(14):9278-9296. doi: 10.1021/acs.jmedchem.3c00449. Epub 2023 Jul 12. J Med Chem. 2023. PMID: 37437222 Free PMC article. Review.
CRISPR screens decode cancer cell pathways that trigger γδ T cell detection.
Mamedov MR, Vedova S, Freimer JW, Sahu AD, Ramesh A, Arce MM, Meringa AD, Ota M, Chen PA, Hanspers K, Nguyen VQ, Takeshima KA, Rios AC, Pritchard JK, Kuball J, Sebestyen Z, Adams EJ, Marson A. Mamedov MR, et al. Nature. 2023 Sep;621(7977):188-195. doi: 10.1038/s41586-023-06482-x. Epub 2023 Aug 30. Nature. 2023. PMID: 37648854 Free PMC article.
The glymphatic system and cerebral small vessel disease.
Ang PS, Zhang DM, Azizi SA, Norton de Matos SA, Brorson JR. Ang PS, et al. J Stroke Cerebrovasc Dis. 2024 Mar;33(3):107557. doi: 10.1016/j.jstrokecerebrovasdis.2024.107557. Epub 2024 Jan 9. J Stroke Cerebrovasc Dis. 2024. PMID: 38198946 Free PMC article. Review.
A pairwise cytokine code explains the organism-wide response to sepsis.
Takahama M, Patil A, Richey G, Cipurko D, Johnson K, Carbonetto P, Plaster M, Pandey S, Cheronis K, Ueda T, Gruenbaum A, Kawamoto T, Stephens M, Chevrier N. Takahama M, et al. Nat Immunol. 2024 Feb;25(2):226-239. doi: 10.1038/s41590-023-01722-8. Epub 2024 Jan 8. Nat Immunol. 2024. PMID: 38191855 Free PMC article.
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker.
Mansurov A, Hosseinchi P, Chang K, Lauterbach AL, Gray LT, Alpar AT, Budina E, Slezak AJ, Kang S, Cao S, Solanki A, Gomes S, Williford JM, Swartz MA, Mendoza JL, Ishihara J, Hubbell JA. Mansurov A, et al. Nat Biomed Eng. 2022 Jul;6(7):819-829. doi: 10.1038/s41551-022-00888-0. Epub 2022 May 9. Nat Biomed Eng. 2022. PMID: 35534574 Free PMC article.
55 results