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31 results

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A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer.
Tanton H, Sewastianik T, Seo HS, Remillard D, Pierre RS, Bala P, Aitymbayev D, Dennis P, Adler K, Geffken E, Yeoh Z, Vangos N, Garbicz F, Scott D, Sethi N, Bradner J, Dhe-Paganon S, Carrasco RD. Tanton H, et al. Sci Adv. 2022 Apr 29;8(17):eabm3108. doi: 10.1126/sciadv.abm3108. Epub 2022 Apr 29. Sci Adv. 2022. PMID: 35486727 Free PMC article.
Enabling Broader Adoption of Biocatalysis in Organic Chemistry.
Romero EO, Saucedo AT, Hernández-Meléndez JR, Yang D, Chakrabarty S, Narayan ARH. Romero EO, et al. JACS Au. 2023 Jul 19;3(8):2073-2085. doi: 10.1021/jacsau.3c00263. eCollection 2023 Aug 28. JACS Au. 2023. PMID: 37654599 Free PMC article. Review.
Conserved 5-methyluridine tRNA modification modulates ribosome translocation.
Jones JD, Franco MK, Giles RN, Eyler DE, Tardu M, Smith TJ, Snyder LR, Polikanov YS, Kennedy RT, Niederer RO, Koutmou KS. Jones JD, et al. Proc Natl Acad Sci U S A. 2024 Aug 27;121(35):e2401743121. doi: 10.1073/pnas.2401743121. Epub 2024 Aug 19. Proc Natl Acad Sci U S A. 2024. PMID: 39159370
MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer.
Augert A, Mathsyaraja H, Ibrahim AH, Freie B, Geuenich MJ, Cheng PF, Alibeckoff SP, Wu N, Hiatt JB, Basom R, Gazdar A, Sullivan LB, Eisenman RN, MacPherson D. Augert A, et al. Cancer Cell. 2020 Jul 13;38(1):97-114.e7. doi: 10.1016/j.ccell.2020.04.016. Epub 2020 May 28. Cancer Cell. 2020. PMID: 32470392 Free PMC article.
Sulfide oxidation promotes hypoxic angiogenesis and neovascularization.
Kumar R, Vitvitsky V, Sethaudom A, Singhal R, Solanki S, Alibeckoff S, Hiraki HL, Bell HN, Andren A, Baker BM, Lyssiotis CA, Shah YM, Banerjee R. Kumar R, et al. Nat Chem Biol. 2024 Oct;20(10):1294-1304. doi: 10.1038/s41589-024-01583-8. Epub 2024 Mar 20. Nat Chem Biol. 2024. PMID: 38509349
31 results