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The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.
Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ. Christov PP, et al. Chem Res Toxicol. 2010 Jun 21;23(6):1076-88. doi: 10.1021/tx100053n. Chem Res Toxicol. 2010. PMID: 20377178 Free PMC article.