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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2000 4
2002 1
2003 1
2007 2
2008 2
2009 11
2010 4
2011 11
2012 10
2013 16
2014 12
2015 18
2016 14
2017 11
2018 10
2019 14
2020 12
2021 6
2022 9
2023 8
2024 1

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166 results

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Page 1
Target identification using drug affinity responsive target stability (DARTS).
Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J. Lomenick B, et al. Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21984-9. doi: 10.1073/pnas.0910040106. Epub 2009 Dec 7. Proc Natl Acad Sci U S A. 2009. PMID: 19995983 Free PMC article.
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.
Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. Chin RM, et al. Nature. 2014 Jun 19;510(7505):397-401. doi: 10.1038/nature13264. Epub 2014 May 14. Nature. 2014. PMID: 24828042 Free PMC article.
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Abskharon R, et al. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2300258120. doi: 10.1073/pnas.2300258120. Epub 2023 Oct 6. Proc Natl Acad Sci U S A. 2023. PMID: 37801475 Free PMC article.
Perfluorocarbons in Chemical Biology.
Miller MA, Sletten EM. Miller MA, et al. Chembiochem. 2020 Dec 11;21(24):3451-3462. doi: 10.1002/cbic.202000297. Epub 2020 Aug 5. Chembiochem. 2020. PMID: 32628804 Free PMC article. Review.
Synthesis of 8-Hydroxygeraniol.
Ippoliti FM, Barber JS, Tang Y, Garg NK. Ippoliti FM, et al. J Org Chem. 2018 Sep 21;83(18):11323-11326. doi: 10.1021/acs.joc.8b01544. Epub 2018 Jul 23. J Org Chem. 2018. PMID: 29969566 Free PMC article.
Coenzyme Q10 deficiencies: pathways in yeast and humans.
Awad AM, Bradley MC, Fernández-Del-Río L, Nag A, Tsui HS, Clarke CF. Awad AM, et al. Essays Biochem. 2018 Jul 20;62(3):361-376. doi: 10.1042/EBC20170106. Print 2018 Jul 20. Essays Biochem. 2018. PMID: 29980630 Free PMC article. Review.
Photorearrangement of [8]-2,6-Pyridinophane N-Oxide.
Hurlow EE, Lin JB, Dweck MJ, Nuryyeva S, Feng Z, Allred TK, Houk KN, Harran PG. Hurlow EE, et al. J Am Chem Soc. 2020 Dec 9;142(49):20717-20724. doi: 10.1021/jacs.0c09310. Epub 2020 Nov 23. J Am Chem Soc. 2020. PMID: 33226803
Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation.
Gao SS, Garcia-Borràs M, Barber JS, Hai Y, Duan A, Garg NK, Houk KN, Tang Y. Gao SS, et al. J Am Chem Soc. 2017 Mar 15;139(10):3639-3642. doi: 10.1021/jacs.7b01089. Epub 2017 Mar 1. J Am Chem Soc. 2017. PMID: 28240554 Free PMC article.
166 results