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Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase.
Protein Sci. 2004 Mar;13(3):763-72. doi: 10.1110/ps.03117204. Epub 2004 Feb 6.
Protein Sci. 2004.
PMID: 14767072
Free PMC article.
Quantitative chimeric analysis of six specificity determinants that differentiate Escherichia coli aspartate from tyrosine aminotransferase.
Shaffer WA, Luong TN, Rothman SC, Kirsch JF.
Shaffer WA, et al.
Protein Sci. 2002 Dec;11(12):2848-59. doi: 10.1110/ps.0221902.
Protein Sci. 2002.
PMID: 12441383
Free PMC article.
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