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Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells.
Jia Q, Liu B, Dang X, Guo Y, Han X, Song T, Cheng JC, Fang L. Jia Q, et al. Reprod Biol Endocrinol. 2022 Feb 19;20(1):34. doi: 10.1186/s12958-022-00912-7. Reprod Biol Endocrinol. 2022. PMID: 35183204 Free PMC article.
However, whether similar results can be observed for the GDF-11 needs to be determined. METHODS: The effect of GDF-11 on StAR expression and the underlying molecular mechanisms were explored by a series of in vitro experiments in a primary culture of hGL cells obtained fro …
However, whether similar results can be observed for the GDF-11 needs to be determined. METHODS: The effect of GDF-11 on StAR express …
TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway.
Fang L, Yan Y, Gao Y, Wu Z, Wang Z, Yang S, Cheng JC, Sun YP. Fang L, et al. Reprod Biol Endocrinol. 2022 Jan 31;20(1):22. doi: 10.1186/s12958-022-00902-9. Reprod Biol Endocrinol. 2022. PMID: 35101033 Free PMC article.
However, whether kisspeptin is regulated by TGF-beta1 and mediates TGF-beta1-suppressed human EVT cell invasion remains unclear. METHODS: The effect of TGF-beta1 on kisspeptin expression and the underlying mechanisms were explored by a series of in vitro experiments in a h …
However, whether kisspeptin is regulated by TGF-beta1 and mediates TGF-beta1-suppressed human EVT cell invasion remains unclear. METHODS