TGF-β1 inhibits human trophoblast cell invasion by upregulating kisspeptin expression through ERK1/2 but not SMAD signaling pathway.
Fang L, Yan Y, Gao Y, Wu Z, Wang Z, Yang S, Cheng JC, Sun YP.
Fang L, et al.
Reprod Biol Endocrinol. 2022 Jan 31;20(1):22. doi: 10.1186/s12958-022-00902-9.
Reprod Biol Endocrinol. 2022.
PMID: 35101033
Free PMC article.
However, whether kisspeptin is regulated by TGF-beta1 and mediates TGF-beta1-suppressed human EVT cell invasion remains unclear. METHODS: The effect of TGF-beta1 on kisspeptin expression and the underlying mechanisms were explored by a series of in vitro experiments in a h …
However, whether kisspeptin is regulated by TGF-beta1 and mediates TGF-beta1-suppressed human EVT cell invasion remains unclear. METHODS …