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Year Number of Results
2020 1
2021 3
2022 3
2023 4
2024 9

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20 results

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Page 1
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer.
Guarducci C, Nardone A, Russo D, Nagy Z, Heraud C, Grinshpun A, Zhang Q, Freelander A, Leventhal MJ, Feit A, Cohen Feit G, Feiglin A, Liu W, Hermida-Prado F, Kesten N, Ma W, De Angelis C, Morlando A, O'Donnell M, Naumenko S, Huang S, Nguyen QD, Huang Y, Malorni L, Bergholz JS, Zhao JJ, Fraenkel E, Lim E, Schiff R, Shapiro GI, Jeselsohn R. Guarducci C, et al. Clin Cancer Res. 2024 May 1;30(9):1889-1905. doi: 10.1158/1078-0432.CCR-23-2975. Clin Cancer Res. 2024. PMID: 38381406 Free PMC article.
The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer.
Amara CS, Kami Reddy KR, Yuntao Y, Chan YS, Piyarathna DWB, Dobrolecki LE, Shih DJH, Shi Z, Xu J, Huang S, Ellis MJ, Apolo AB, Ballester LY, Gao J, Hansel DE, Lotan Y, Hodges HC, Lerner SP, Creighton CJ, Sreekumar A, Zheng WJ, Msaouel P, Kavuri SM, Putluri N. Amara CS, et al. Nat Commun. 2024 Feb 14;15(1):1373. doi: 10.1038/s41467-024-45132-2. Nat Commun. 2024. PMID: 38355560 Free PMC article.
Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer.
Yue F, Ku AT, Stevens PD, Michalski MN, Jiang W, Tu J, Shi Z, Dou Y, Wang Y, Feng XH, Hostetter G, Wu X, Huang S, Shroyer NF, Zhang B, Williams BO, Liu Q, Lin X, Li Y. Yue F, et al. bioRxiv [Preprint]. 2024 Jan 11:2024.01.10.574969. doi: 10.1101/2024.01.10.574969. bioRxiv. 2024. PMID: 38260423 Free PMC article. Preprint.
SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
Zhang L, Hsu JI, Braekeleer ED, Chen CW, Patel TD, Martell AG, Guzman AG, Wohlan K, Waldvogel SM, Urya H, Tovy A, Callen E, Murdaugh R, Richard R, Jansen S, Vissers L, de Vries BBA, Nussenzweig A, Huang S, Coarfa C, Anastas JN, Takahashi K, Vassiliou G, Goodell MA. Zhang L, et al. bioRxiv [Preprint]. 2024 Jan 17:2023.08.31.555634. doi: 10.1101/2023.08.31.555634. bioRxiv. 2024. Update in: Elife. 2024 Jun 18;12:RP91611. doi: 10.7554/eLife.91611. PMID: 37693622 Free PMC article. Updated. Preprint.
A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis.
Yue F, Jiang W, Ku AT, Young AIJ, Zhang W, Souto EP, Gao Y, Yu Z, Wang Y, Creighton CJ, Nagi C, Wang T, Hilsenbeck SG, Feng XH, Huang S, Coarfa C, Zhang XH, Liu Q, Lin X, Li Y. Yue F, et al. Cancer Res. 2021 Sep 1;81(17):4441-4454. doi: 10.1158/0008-5472.CAN-21-1112. Epub 2021 Jun 7. Cancer Res. 2021. PMID: 34099494 Free PMC article.
SOD1 is a synthetic-lethal target in PPM1D-mutant leukemia cells.
Zhang L, Hsu JI, Braekeleer ED, Chen CW, Patel TD, Martell AG, Guzman AG, Wohlan K, Waldvogel SM, Uryu H, Tovy A, Callen E, Murdaugh RL, Richard R, Jansen S, Vissers L, de Vries BBA, Nussenzweig A, Huang S, Coarfa C, Anastas J, Takahashi K, Vassiliou G, Goodell MA. Zhang L, et al. Elife. 2024 Jun 18;12:RP91611. doi: 10.7554/eLife.91611. Elife. 2024. PMID: 38896450 Free PMC article.
Dextran Sulfate Polymer Wafer Promotes Corneal Wound Healing.
Ammassam Veettil R, Marcano DC, Yuan X, Zaheer M, Adumbumkulath A, Lee R, Isenhart LC, Soriano N, Mhatre K, Joseph R, Mani SA, Shin CS, Acharya G. Ammassam Veettil R, et al. Pharmaceutics. 2021 Oct 6;13(10):1628. doi: 10.3390/pharmaceutics13101628. Pharmaceutics. 2021. PMID: 34683921 Free PMC article.
Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia.
Sakthivel D, Brown-Suedel AN, Lopez KE, Salgar S, Coutinho LE, Keane F, Huang S, Sherry KM, Charendoff CI, Dunne KP, Robichaux DJ, Vargas-Hernández A, Le B, Shin CS, Carisey AF, Poreba M, Flanagan JM, Bouchier-Hayes L. Sakthivel D, et al. Sci Adv. 2024 Aug 2;10(31):eadj3145. doi: 10.1126/sciadv.adj3145. Epub 2024 Aug 2. Sci Adv. 2024. PMID: 39093977 Free PMC article.
20 results