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2022 4
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity.
Andrews LP, Butler SC, Cui J, Cillo AR, Cardello C, Liu C, Brunazzi EA, Baessler A, Xie B, Kunning SR, Ngiow SF, Huang YJ, Manne S, Sharpe AH, Delgoffe GM, Wherry EJ, Kirkwood JM, Bruno TC, Workman CJ, Vignali DAA. Andrews LP, et al. Cell. 2024 Aug 8;187(16):4355-4372.e22. doi: 10.1016/j.cell.2024.07.016. Cell. 2024. PMID: 39121848
IFNγ-induction of TH1-like regulatory T cells controls antiviral responses.
Gocher-Demske AM, Cui J, Szymczak-Workman AL, Vignali KM, Latini JN, Pieklo GP, Kimball JC, Avery L, Cipolla EM, Huckestein BR, Hedden L, Meisel M, Alcorn JF, Kane LP, Workman CJ, Vignali DAA. Gocher-Demske AM, et al. Nat Immunol. 2023 May;24(5):841-854. doi: 10.1038/s41590-023-01453-w. Epub 2023 Mar 16. Nat Immunol. 2023. PMID: 36928412 Free PMC article.
p38MAPKα Stromal Reprogramming Sensitizes Metastatic Breast Cancer to Immunotherapy.
Faget DV, Luo X, Inkman MJ, Ren Q, Su X, Ding K, Waters MR, Raut GK, Pandey G, Dodhiawala PB, Ramalho-Oliveira R, Ye J, Cole T, Murali B, Zheleznyak A, Shokeen M, Weiss KR, Monahan JB, DeSelm CJ, Lee AV, Oesterreich S, Weilbaecher KN, Zhang J, DeNardo DG, Stewart SA. Faget DV, et al. Cancer Discov. 2023 Jun 2;13(6):1454-1477. doi: 10.1158/2159-8290.CD-22-0907. Cancer Discov. 2023. PMID: 36883955 Free PMC article.
Single-nucleus chromatin accessibility identifies a critical role for TWIST1 in idiopathic pulmonary fibrosis myofibroblast activity.
Valenzi E, Bahudhanapati H, Tan J, Tabib T, Sullivan DI, Nouraie M, Sembrat J, Fan L, Chen K, Liu S, Rojas M, Lafargue A, Felsher DW, Tran PT, Kass DJ, Lafyatis R. Valenzi E, et al. Eur Respir J. 2023 Jul 7;62(1):2200474. doi: 10.1183/13993003.00474-2022. Print 2023 Jul. Eur Respir J. 2023. PMID: 37142338 Free PMC article.
Drosha-dependent microRNAs modulate FUS-mediated neurodegeneration in vivo.
Kour S, Fortuna T, Anderson EN, Mawrie D, Bilstein J, Sivasubramanian R, Ward C, Roy R, Rajasundaram D, Sterneckert J, Pandey UB. Kour S, et al. Nucleic Acids Res. 2023 Nov 10;51(20):11258-11276. doi: 10.1093/nar/gkad774. Nucleic Acids Res. 2023. PMID: 37791873 Free PMC article.
Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma.
Augustin RC, Newman S, Li A, Joy M, Lyons M, Pham MP, Lucas P, Smith K, Sander C, Isett B, Davar D, Najjar YG, Zarour HM, Kirkwood JM, Luke JJ, Bao R. Augustin RC, et al. J Immunother Cancer. 2023 Oct;11(10):e007567. doi: 10.1136/jitc-2023-007567. J Immunother Cancer. 2023. PMID: 37857525 Free PMC article.
Psoriatic arthritis subtypes are phenocopied in humanized mice.
Ritchlin CT, Rangel-Moreno J, Martino D, Isett B, Paine A, Bhattacharya S, Fox J, Meyer EM, Bao R, Bruno T, Tausk F, de la Luz Garcia-Hernandez M. Ritchlin CT, et al. JCI Insight. 2024 Jul 2;9(15):e178213. doi: 10.1172/jci.insight.178213. JCI Insight. 2024. PMID: 39114979 Free PMC article.
Uveal melanoma immunogenomics predict immunotherapy resistance and susceptibility.
Leonard-Murali S, Bhaskarla C, Yadav GS, Maurya SK, Galiveti CR, Tobin JA, Kann RJ, Ashwat E, Murphy PS, Chakka AB, Soman V, Cantalupo PG, Zhuo X, Vyas G, Kozak DL, Kelly LM, Smith E, Chandran UR, Hsu YS, Kammula US. Leonard-Murali S, et al. Nat Commun. 2024 Apr 16;15(1):2863. doi: 10.1038/s41467-024-46906-4. Nat Commun. 2024. PMID: 38627362 Free PMC article.
107 results