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Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals.
Amin N, Liu J, Bonnechere B, MahmoudianDehkordi S, Arnold M, Batra R, Chiou YJ, Fernandes M, Ikram MA, Kraaij R, Krumsiek J, Newby D, Nho K, Radjabzadeh D, Saykin AJ, Shi L, Sproviero W, Winchester L, Yang Y, Nevado-Holgado AJ, Kastenmüller G, Kaddurah-Daouk R, van Duijn CM. Amin N, et al. JAMA Psychiatry. 2023 Jun 1;80(6):597-609. doi: 10.1001/jamapsychiatry.2023.0685. JAMA Psychiatry. 2023. PMID: 37074710 Free PMC article.
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
Horgusluoglu E, Neff R, Song WM, Wang M, Wang Q, Arnold M, Krumsiek J, Galindo-Prieto B, Ming C, Nho K, Kastenmüller G, Han X, Baillie R, Zeng Q, Andrews S, Cheng H, Hao K, Goate A, Bennett DA, Saykin AJ, Kaddurah-Daouk R, Zhang B; Alzheimer's Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Metabolomics Consortium. Horgusluoglu E, et al. Alzheimers Dement. 2022 Jun;18(6):1260-1278. doi: 10.1002/alz.12468. Epub 2021 Nov 10. Alzheimers Dement. 2022. PMID: 34757660 Free PMC article.
Metabolomic and inflammatory signatures of symptom dimensions in major depression.
Brydges CR, Bhattacharyya S, Dehkordi SM, Milaneschi Y, Penninx B, Jansen R, Kristal BS, Han X, Arnold M, Kastenmüller G, Bekhbat M, Mayberg HS, Craighead WE, Rush AJ, Fiehn O, Dunlop BW, Kaddurah-Daouk R; Mood Disorders Precision Medicine Consortium. Brydges CR, et al. Brain Behav Immun. 2022 May;102:42-52. doi: 10.1016/j.bbi.2022.02.003. Epub 2022 Feb 4. Brain Behav Immun. 2022. PMID: 35131442 Free PMC article.
Genetic architecture of host proteins involved in SARS-CoV-2 infection.
Pietzner M, Wheeler E, Carrasco-Zanini J, Raffler J, Kerrison ND, Oerton E, Auyeung VPW, Luan J, Finan C, Casas JP, Ostroff R, Williams SA, Kastenmüller G, Ralser M, Gamazon ER, Wareham NJ, Hingorani AD, Langenberg C. Pietzner M, et al. Nat Commun. 2020 Dec 16;11(1):6397. doi: 10.1038/s41467-020-19996-z. Nat Commun. 2020. PMID: 33328453 Free PMC article.
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
Jo T, Kim J, Bice P, Huynh K, Wang T, Arnold M, Meikle PJ, Giles C, Kaddurah-Daouk R, Saykin AJ, Nho K; Alzheimer's Disease Metabolomics Consortium (ADMC); Alzheimer's Disease Neuroimaging Initiative (ADNI). Jo T, et al. EBioMedicine. 2023 Nov;97:104820. doi: 10.1016/j.ebiom.2023.104820. Epub 2023 Oct 7. EBioMedicine. 2023. PMID: 37806288 Free PMC article.
Serum Bile Acids Improve Prediction of Alzheimer's Progression in a Sex-Dependent Manner.
Chen T, Wang L, Xie G, Kristal BS, Zheng X, Sun T, Arnold M, Louie G, Li M, Wu L, Mahmoudiandehkordi S, Sniatynski MJ, Borkowski K, Guo Q, Kuang J, Wang J, Nho K, Ren Z, Kueider-Paisley A, Blach C, Kaddurah-Daouk R, Jia W; Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Alzheimer Disease Metabolomics Consortium (ADMC). Chen T, et al. Adv Sci (Weinh). 2024 Mar;11(9):e2306576. doi: 10.1002/advs.202306576. Epub 2023 Dec 13. Adv Sci (Weinh). 2024. PMID: 38093507 Free PMC article.
The Metabolome-Wide Signature of Major Depressive Disorder.
Jansen R, Milaneschi Y, Schranner D, Kastenmuller G, Arnold M, Han X, Dunlop BW; Mood Disorder Precision Medicine Consortium; Rush AJ, Kaddurah-Daouk R, Penninx BW. Jansen R, et al. Res Sq [Preprint]. 2023 Sep 21:rs.3.rs-3127544. doi: 10.21203/rs.3.rs-3127544/v1. Res Sq. 2023. Update in: Mol Psychiatry. 2024 Dec;29(12):3722-3733. doi: 10.1038/s41380-024-02613-6 PMID: 37790319 Free PMC article. Updated. Preprint.
68 results