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Page 1
The central moTOR of metabolism.
Simcox J, Lamming DW. Simcox J, et al. Dev Cell. 2022 Mar 28;57(6):691-706. doi: 10.1016/j.devcel.2022.02.024. Epub 2022 Mar 21. Dev Cell. 2022. PMID: 35316619 Free PMC article. Review.
Targeting the biology of aging with mTOR inhibitors.
Mannick JB, Lamming DW. Mannick JB, et al. Nat Aging. 2023 Jun;3(6):642-660. doi: 10.1038/s43587-023-00416-y. Epub 2023 May 4. Nat Aging. 2023. PMID: 37142830 Free PMC article. Review.
Dietary restriction of isoleucine increases healthspan and lifespan of genetically heterogeneous mice.
Green CL, Trautman ME, Chaiyakul K, Jain R, Alam YH, Babygirija R, Pak HH, Sonsalla MM, Calubag MF, Yeh CY, Bleicher A, Novak G, Liu TT, Newman S, Ricke WA, Matkowskyj KA, Ong IM, Jang C, Simcox J, Lamming DW. Green CL, et al. Cell Metab. 2023 Nov 7;35(11):1976-1995.e6. doi: 10.1016/j.cmet.2023.10.005. Cell Metab. 2023. PMID: 37939658 Free PMC article.
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine.
Yu D, Richardson NE, Green CL, Spicer AB, Murphy ME, Flores V, Jang C, Kasza I, Nikodemova M, Wakai MH, Tomasiewicz JL, Yang SE, Miller BR, Pak HH, Brinkman JA, Rojas JM, Quinn WJ 3rd, Cheng EP, Konon EN, Haider LR, Finke M, Sonsalla M, Alexander CM, Rabinowitz JD, Baur JA, Malecki KC, Lamming DW. Yu D, et al. Cell Metab. 2021 May 4;33(5):905-922.e6. doi: 10.1016/j.cmet.2021.03.025. Epub 2021 Apr 21. Cell Metab. 2021. PMID: 33887198 Free PMC article.
ARDD 2020: from aging mechanisms to interventions.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. Mkrtchyan GV, et al. Aging (Albany NY). 2020 Dec 30;12(24):24484-24503. doi: 10.18632/aging.202454. Epub 2020 Dec 30. Aging (Albany NY). 2020. PMID: 33378272 Free PMC article. Review.
When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging.
Mihaylova MM, Chaix A, Delibegovic M, Ramsey JJ, Bass J, Melkani G, Singh R, Chen Z, Ja WW, Shirasu-Hiza M, Latimer MN, Mattison JA, Thalacker-Mercer AE, Dixit VD, Panda S, Lamming DW. Mihaylova MM, et al. Cell Metab. 2023 Jul 11;35(7):1114-1131. doi: 10.1016/j.cmet.2023.06.008. Epub 2023 Jun 30. Cell Metab. 2023. PMID: 37392742 Free PMC article. Review.
44 results