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Page 1
Senescent alveolar macrophages promote early-stage lung tumorigenesis.
Prieto LI, Sturmlechner I, Graves SI, Zhang C, Goplen NP, Yi ES, Sun J, Li H, Baker DJ. Prieto LI, et al. Cancer Cell. 2023 Jul 10;41(7):1261-1275.e6. doi: 10.1016/j.ccell.2023.05.006. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267954 Free PMC article.
Protein Phase Separation: A New Phase in Cell Biology.
Boeynaems S, Alberti S, Fawzi NL, Mittag T, Polymenidou M, Rousseau F, Schymkowitz J, Shorter J, Wolozin B, Van Den Bosch L, Tompa P, Fuxreiter M. Boeynaems S, et al. Trends Cell Biol. 2018 Jun;28(6):420-435. doi: 10.1016/j.tcb.2018.02.004. Epub 2018 Mar 27. Trends Cell Biol. 2018. PMID: 29602697 Free PMC article. Review.
Stress granules and neurodegeneration.
Wolozin B, Ivanov P. Wolozin B, et al. Nat Rev Neurosci. 2019 Nov;20(11):649-666. doi: 10.1038/s41583-019-0222-5. Epub 2019 Oct 3. Nat Rev Neurosci. 2019. PMID: 31582840 Free PMC article. Review.
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Pourhaghighi R, Ash PEA, Phanse S, Goebels F, Hu LZM, Chen S, Zhang Y, Wierbowski SD, Boudeau S, Moutaoufik MT, Malty RH, Malolepsza E, Tsafou K, Nathan A, Cromar G, Guo H, Abdullatif AA, Apicco DJ, Becker LA, Gitler AD, Pulst SM, Youssef A, Hekman R, Havugimana PC, White CA, Blum BC, Ratti A, Bryant CD, Parkinson J, Lage K, Babu M, Yu H, Bader GD, Wolozin B, Emili A. Pourhaghighi R, et al. Cell Syst. 2020 Apr 22;10(4):333-350.e14. doi: 10.1016/j.cels.2020.03.003. Cell Syst. 2020. PMID: 32325033 Free PMC article.
p21 produces a bioactive secretome that places stressed cells under immunosurveillance.
Sturmlechner I, Zhang C, Sine CC, van Deursen EJ, Jeganathan KB, Hamada N, Grasic J, Friedman D, Stutchman JT, Can I, Hamada M, Lim DY, Lee JH, Ordog T, Laberge RM, Shapiro V, Baker DJ, Li H, van Deursen JM. Sturmlechner I, et al. Science. 2021 Oct 29;374(6567):eabb3420. doi: 10.1126/science.abb3420. Epub 2021 Oct 29. Science. 2021. PMID: 34709885 Free PMC article.
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.
Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, Abisambra JF, Kuo MH, Kanaan N, Murray ME, Crary JF, Zhao J, Cheng JX, Petrucelli L, Li H, Emili A, Wolozin B. Jiang L, et al. Mol Cell. 2021 Oct 21;81(20):4209-4227.e12. doi: 10.1016/j.molcel.2021.07.038. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453888 Free PMC article.
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.
Ash PEA, Lei S, Shattuck J, Boudeau S, Carlomagno Y, Medalla M, Mashimo BL, Socorro G, Al-Mohanna LFA, Jiang L, Öztürk MM, Knobel M, Ivanov P, Petrucelli L, Wegmann S, Kanaan NM, Wolozin B. Ash PEA, et al. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2014188118. doi: 10.1073/pnas.2014188118. Proc Natl Acad Sci U S A. 2021. PMID: 33619090 Free PMC article.
Protein Interaction Network Biology in Neuroscience.
Basu A, Ash PE, Wolozin B, Emili A. Basu A, et al. Proteomics. 2021 Feb;21(3-4):e1900311. doi: 10.1002/pmic.201900311. Epub 2020 Dec 29. Proteomics. 2021. PMID: 33314619 Free PMC article. Review.
58 results