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Ferroptosis: mechanisms, biology and role in disease.
Jiang X, Stockwell BR, Conrad M. Jiang X, et al. Nat Rev Mol Cell Biol. 2021 Apr;22(4):266-282. doi: 10.1038/s41580-020-00324-8. Epub 2021 Jan 25. Nat Rev Mol Cell Biol. 2021. PMID: 33495651 Free PMC article. Review.
Energy-stress-mediated AMPK activation inhibits ferroptosis.
Lee H, Zandkarimi F, Zhang Y, Meena JK, Kim J, Zhuang L, Tyagi S, Ma L, Westbrook TF, Steinberg GR, Nakada D, Stockwell BR, Gan B. Lee H, et al. Nat Cell Biol. 2020 Feb;22(2):225-234. doi: 10.1038/s41556-020-0461-8. Epub 2020 Feb 6. Nat Cell Biol. 2020. PMID: 32029897 Free PMC article.
Emerging Mechanisms and Disease Relevance of Ferroptosis.
Stockwell BR, Jiang X, Gu W. Stockwell BR, et al. Trends Cell Biol. 2020 Jun;30(6):478-490. doi: 10.1016/j.tcb.2020.02.009. Epub 2020 Mar 21. Trends Cell Biol. 2020. PMID: 32413317 Free PMC article. Review.
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.
Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, Saito Y, Savage T, Wells RG, Mack M, Zender L, Arpaia N, Remotti HE, Rabadan R, Sims P, Leblond AL, Weber A, Riener MO, Stockwell BR, Gaublomme J, Llovet JM, Kalluri R, Michalopoulos GK, Seki E, Sia D, Chen X, Califano A, Schwabe RF. Affo S, et al. Cancer Cell. 2021 Jun 14;39(6):866-882.e11. doi: 10.1016/j.ccell.2021.03.012. Epub 2021 Apr 29. Cancer Cell. 2021. PMID: 33930309 Free PMC article.
SnapShot: Ferroptosis.
Hadian K, Stockwell BR. Hadian K, et al. Cell. 2020 May 28;181(5):1188-1188.e1. doi: 10.1016/j.cell.2020.04.039. Cell. 2020. PMID: 32470402 Free PMC article.
Transferrin Receptor Is a Specific Ferroptosis Marker.
Feng H, Schorpp K, Jin J, Yozwiak CE, Hoffstrom BG, Decker AM, Rajbhandari P, Stokes ME, Bender HG, Csuka JM, Upadhyayula PS, Canoll P, Uchida K, Soni RK, Hadian K, Stockwell BR. Feng H, et al. Cell Rep. 2020 Mar 10;30(10):3411-3423.e7. doi: 10.1016/j.celrep.2020.02.049. Cell Rep. 2020. PMID: 32160546 Free PMC article.
GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling.
Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Müller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kössl J, Brandner S, Daniels JD, Schmitt-Kopplin P, Hauck SM, Stockwell BR, Hadian K, Schick JA. Kraft VAN, et al. ACS Cent Sci. 2020 Jan 22;6(1):41-53. doi: 10.1021/acscentsci.9b01063. Epub 2019 Dec 27. ACS Cent Sci. 2020. PMID: 31989025 Free PMC article.
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism.
Upadhyayula PS, Higgins DM, Mela A, Banu M, Dovas A, Zandkarimi F, Patel P, Mahajan A, Humala N, Nguyen TTT, Chaudhary KR, Liao L, Argenziano M, Sudhakar T, Sperring CP, Shapiro BL, Ahmed ER, Kinslow C, Ye LF, Siegelin MD, Cheng S, Soni R, Bruce JN, Stockwell BR, Canoll P. Upadhyayula PS, et al. Nat Commun. 2023 Mar 2;14(1):1187. doi: 10.1038/s41467-023-36630-w. Nat Commun. 2023. PMID: 36864031 Free PMC article.
MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling.
Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, Prives C, Stockwell BR. Venkatesh D, et al. Genes Dev. 2020 Apr 1;34(7-8):526-543. doi: 10.1101/gad.334219.119. Epub 2020 Feb 20. Genes Dev. 2020. PMID: 32079652 Free PMC article.
25 results