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Optimization of an alum-anchored clinical HIV vaccine candidate.
Rodrigues KA, Cottrell CA, Steichen JM, Groschel B, Abraham W, Suh H, Agarwal Y, Ni K, Chang JYH, Yousefpour P, Melo MB, Schief WR, Irvine DJ. Rodrigues KA, et al. NPJ Vaccines. 2023 Aug 12;8(1):117. doi: 10.1038/s41541-023-00711-0. NPJ Vaccines. 2023. PMID: 37573422 Free PMC article.
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.
Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ. Silva M, et al. Sci Immunol. 2021 Dec 3;6(66):eabf1152. doi: 10.1126/sciimmunol.abf1152. Epub 2021 Dec 3. Sci Immunol. 2021. PMID: 34860581 Free PMC article.
Two-dose "extended priming" immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response.
Bhagchandani SH, Yang L, Maiorino L, Ben-Akiva E, Rodrigues KA, Romanov A, Suh H, Aung A, Wu S, Wadhera A, Chakraborty AK, Irvine DJ. Bhagchandani SH, et al. bioRxiv [Preprint]. 2023 Nov 21:2023.11.20.563479. doi: 10.1101/2023.11.20.563479. bioRxiv. 2023. Update in: Sci Immunol. 2024 Sep 20;9(99):eadl3755. doi: 10.1126/sciimmunol.adl3755 PMID: 38045401 Free PMC article. Updated. Preprint.
Biomaterials-Mediated Engineering of the Immune System.
Backlund C, Jalili-Firoozinezhad S, Kim B, Irvine DJ. Backlund C, et al. Annu Rev Immunol. 2023 Apr 26;41:153-179. doi: 10.1146/annurev-immunol-101721-040259. Epub 2023 Jan 25. Annu Rev Immunol. 2023. PMID: 36696570 Free PMC article. Review.
13 results