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Page 1
mTOR at the nexus of nutrition, growth, ageing and disease.
Liu GY, Sabatini DM. Liu GY, et al. Nat Rev Mol Cell Biol. 2020 Apr;21(4):183-203. doi: 10.1038/s41580-019-0199-y. Epub 2020 Jan 14. Nat Rev Mol Cell Biol. 2020. PMID: 31937935 Free PMC article. Review.
mTOR signaling in growth control and disease.
Laplante M, Sabatini DM. Laplante M, et al. Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017. Cell. 2012. PMID: 22500797 Free PMC article. Review.
Nutrient-sensing mechanisms and pathways.
Efeyan A, Comb WC, Sabatini DM. Efeyan A, et al. Nature. 2015 Jan 15;517(7534):302-10. doi: 10.1038/nature14190. Nature. 2015. PMID: 25592535 Free PMC article. Review.
Nutrient regulation of mTORC1 at a glance.
Condon KJ, Sabatini DM. Condon KJ, et al. J Cell Sci. 2019 Nov 13;132(21):jcs222570. doi: 10.1242/jcs.222570. J Cell Sci. 2019. PMID: 31722960 Free PMC article. Review.
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH. Beyaz S, et al. Nature. 2016 Mar 3;531(7592):53-8. doi: 10.1038/nature17173. Nature. 2016. PMID: 26935695 Free PMC article.
MCART1/SLC25A51 is required for mitochondrial NAD transport.
Kory N, Uit de Bos J, van der Rijt S, Jankovic N, Güra M, Arp N, Pena IA, Prakash G, Chan SH, Kunchok T, Lewis CA, Sabatini DM. Kory N, et al. Sci Adv. 2020 Oct 21;6(43):eabe5310. doi: 10.1126/sciadv.abe5310. Print 2020 Oct. Sci Adv. 2020. PMID: 33087354 Free PMC article.
The TSC-mTOR pathway regulates macrophage polarization.
Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, Horng T. Byles V, et al. Nat Commun. 2013;4:2834. doi: 10.1038/ncomms3834. Nat Commun. 2013. PMID: 24280772 Free PMC article.
NUFIP1 is a ribosome receptor for starvation-induced ribophagy.
Wyant GA, Abu-Remaileh M, Frenkel EM, Laqtom NN, Dharamdasani V, Lewis CA, Chan SH, Heinze I, Ori A, Sabatini DM. Wyant GA, et al. Science. 2018 May 18;360(6390):751-758. doi: 10.1126/science.aar2663. Epub 2018 Apr 26. Science. 2018. PMID: 29700228 Free PMC article.
95 results