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The myosin super-relaxed state is disrupted by estradiol deficiency.
Colson BA, Petersen KJ, Collins BC, Lowe DA, Thomas DD. Colson BA, et al. Biochem Biophys Res Commun. 2015 Jan 2;456(1):151-5. doi: 10.1016/j.bbrc.2014.11.050. Epub 2014 Nov 21. Biochem Biophys Res Commun. 2015. PMID: 25446114 Free PMC article.