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Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress.
Do BT, Hsu PP, Vermeulen SY, Wang Z, Hirz T, Abbott KL, Aziz N, Replogle JM, Bjelosevic S, Paolino J, Nelson SA, Block S, Darnell AM, Ferreira R, Zhang H, Milosevic J, Schmidt DR, Chidley C, Harris IS, Weissman JS, Pikman Y, Stegmaier K, Cheloufi S, Su XA, Sykes DB, Vander Heiden MG. Do BT, et al. Dev Cell. 2024 Aug 19;59(16):2203-2221.e15. doi: 10.1016/j.devcel.2024.05.010. Epub 2024 May 31. Dev Cell. 2024. PMID: 38823395