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17 results

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Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations.
Maillard M, Nishii R, Yang W, Hoshitsuki K, Chepyala D, Lee SHR, Nguyen JQ, Relling MV, Crews KR, Leggas M, Singh M, Suang JLY, Yeoh AEJ, Jeha S, Inaba H, Pui CH, Karol SE, Trehan A, Bhatia P, Antillon Klussmann FG, Bhojwani D, Haidar CE, Yang JJ. Maillard M, et al. J Natl Cancer Inst. 2024 May 8;116(5):702-710. doi: 10.1093/jnci/djae004. J Natl Cancer Inst. 2024. PMID: 38230823
Impact of Age on Pharmacogenomics and Treatment Outcomes of B-Cell Acute Lymphoblastic Leukemia.
Yoshimura S, Li Z, Gocho Y, Yang W, Crews KR, Lee SHR, Roberts KG, Mullighan CG, Relling MV, Yu J, Yeoh AEJ, Loh ML, Saygin C, Litzow MR, Jeha S, Karol SE, Inaba H, Pui CH, Konopleva M, Jain N, Stock W, Paietta E, Jabbour E, Kornblau SM, Evans WE, Yang JJ. Yoshimura S, et al. J Clin Oncol. 2024 Oct 10;42(29):3478-3490. doi: 10.1200/JCO.24.00500. Epub 2024 Aug 5. J Clin Oncol. 2024. PMID: 39102629
Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia.
Huang X, Li Y, Zhang J, Yan L, Zhao H, Ding L, Bhatara S, Yang X, Yoshimura S, Yang W, Karol SE, Inaba H, Mullighan C, Litzow M, Zhu X, Zhang Y, Stock W, Jain N, Jabbour E, Kornblau SM, Konopleva M, Pui CH, Paietta E, Evans W, Yu J, Yang JJ. Huang X, et al. Cancer Cell. 2024 Apr 8;42(4):552-567.e6. doi: 10.1016/j.ccell.2024.03.003. Cancer Cell. 2024. PMID: 38593781 Free PMC article.
Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.
Lee SHR, Yang W, Gocho Y, John A, Rowland L, Smart B, Williams H, Maxwell D, Hunt J, Yang W, Crews KR, Roberts KG, Jeha S, Cheng C, Karol SE, Relling MV, Rosner GL, Inaba H, Mullighan CG, Pui CH, Evans WE, Yang JJ. Lee SHR, et al. Nat Med. 2023 Jan;29(1):170-179. doi: 10.1038/s41591-022-02112-7. Epub 2023 Jan 5. Nat Med. 2023. PMID: 36604538 Free PMC article.
Prognostic and Pharmacotypic Heterogeneity of Hyperdiploidy in Childhood ALL.
Lee SHR, Ashcraft E, Yang W, Roberts KG, Gocho Y, Rowland L, Inaba H, Karol SE, Jeha S, Crews KR, Mullighan CG, Relling MV, Evans WE, Cheng C, Yang JJ, Pui CH. Lee SHR, et al. J Clin Oncol. 2023 Dec 10;41(35):5422-5432. doi: 10.1200/JCO.23.00880. Epub 2023 Sep 20. J Clin Oncol. 2023. PMID: 37729596 Free PMC article.
PharmGKB summary: acyclovir/ganciclovir pathway.
Maillard M, Gong L, Nishii R, Yang JJ, Whirl-Carrillo M, Klein TE. Maillard M, et al. Pharmacogenet Genomics. 2022 Jul 1;32(5):201-208. doi: 10.1097/FPC.0000000000000474. Epub 2022 May 30. Pharmacogenet Genomics. 2022. PMID: 35665708 Free PMC article. No abstract available.
17 results