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Dihydropyridine Lactam Analogs Targeting BET Bromodomains.
Jiang J, Sigua LH, Chan A, Kalra P, Pomerantz WCK, Schönbrunn E, Qi J, Georg GI. Jiang J, et al. ChemMedChem. 2022 Jan 5;17(1):e202100407. doi: 10.1002/cmdc.202100407. Epub 2021 Dec 21. ChemMedChem. 2022. PMID: 34932262 Free PMC article.
From PROTAC to inhibitor: Structure-guided discovery of potent and orally bioavailable BET inhibitors.
Koravovic M, Mayasundari A, Tasic G, Keramatnia F, Stachowski TR, Cui H, Chai SC, Jonchere B, Yang L, Li Y, Fu X, Hiltenbrand R, Paul L, Mishra V, Klco JM, Roussel MF, Pomerantz WC, Fischer M, Rankovic Z, Savic V. Koravovic M, et al. Eur J Med Chem. 2023 May 5;251:115246. doi: 10.1016/j.ejmech.2023.115246. Epub 2023 Mar 4. Eur J Med Chem. 2023. PMID: 36898329 Free PMC article.
Design of Highly Fluorinated Peptides for Cell-based 19F NMR.
Li J, Kirberger SE, Wang Y, Cui H, Wagner CR, Pomerantz WCK. Li J, et al. Bioconjug Chem. 2023 Aug 16;34(8):1477-1485. doi: 10.1021/acs.bioconjchem.3c00245. Epub 2023 Jul 31. Bioconjug Chem. 2023. PMID: 37523271 Free PMC article.
Multivalent Fluorinated Nanorings for On-Cell 19F NMR.
Li J, Wang Y, Distefano MD, Wagner CR, Pomerantz WCK. Li J, et al. Biomacromolecules. 2024 Feb 12;25(2):1330-1339. doi: 10.1021/acs.biomac.3c01391. Epub 2024 Jan 22. Biomacromolecules. 2024. PMID: 38254252 Free PMC article.
Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader.
Divakaran A, Scholtz CR, Zahid H, Lin W, Griffith EC, Lee RE, Chen T, Harki DA, Pomerantz WCK. Divakaran A, et al. ACS Med Chem Lett. 2022 Sep 29;13(10):1621-1627. doi: 10.1021/acsmedchemlett.2c00300. eCollection 2022 Oct 13. ACS Med Chem Lett. 2022. PMID: 36262390 Free PMC article.
21 results