R35 GM137927/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2020	1
2021	2
2022	2
2023	7
2024	3

1

PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade.

Srour N, Villarreal OD, Hardikar S, Yu Z, Preston S, Miller WH Jr, Szewczyk MM, Barsyte-Lovejoy D, Xu H, Chen T, Del Rincón SV, Richard S. Srour N, et al. Cell Rep. 2022 Mar 29;38(13):110582. doi: 10.1016/j.celrep.2022.110582. Cell Rep. 2022. PMID: 35354055 Free PMC article.

2

Multiomics analyses reveal DARS1-AS1/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance.

Zheng C, Wei Y, Zhang Q, Sun M, Wang Y, Hou J, Zhang P, Lv X, Su D, Jiang Y, Gumin J, Sahni N, Hu B, Wang W, Chen X, McGrail DJ, Zhang C, Huang S, Xu H, Chen J, Lang FF, Hu J, Chen Y. Zheng C, et al. Sci Adv. 2023 Aug 4;9(31):eadf3984. doi: 10.1126/sciadv.adf3984. Epub 2023 Aug 4. Sci Adv. 2023. PMID: 37540752 Free PMC article.

3

SART3 reads methylarginine-marked glycine- and arginine-rich motifs.

Wang Y, Zhou J, He W, Fu R, Shi L, Dang NK, Liu B, Xu H, Cheng X, Bedford MT. Wang Y, et al. Cell Rep. 2024 Jul 23;43(7):114459. doi: 10.1016/j.celrep.2024.114459. Epub 2024 Jul 9. Cell Rep. 2024. PMID: 38985674 Free PMC article.

4

CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.

Zheng C, Wei Y, Zhang P, Lin K, He D, Teng H, Manyam G, Zhang Z, Liu W, Lee HRL, Tang X, He W, Islam N, Jain A, Chiu Y, Cao S, Diao Y, Meyer-Gauen S, Höök M, Malovannaya A, Li W, Hu M, Wang W, Xu H, Kopetz S, Chen Y. Zheng C, et al. Nat Struct Mol Biol. 2023 Dec;30(12):1878-1892. doi: 10.1038/s41594-023-01117-1. Epub 2023 Nov 6. Nat Struct Mol Biol. 2023. PMID: 37932451 Free PMC article.

5

MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors.

Chen S, Hou J, Jaffery R, Guerrero A, Fu R, Shi L, Zheng N, Bohat R, Egan NA, Yu C, Sharif S, Lu Y, He W, Wang S, Gjuka D, Stone EM, Shah PA, Rodon Ahnert J, Chen T, Liu X, Bedford MT, Xu H, Peng W. Chen S, et al. J Immunother Cancer. 2024 Sep 23;12(9):e009600. doi: 10.1136/jitc-2024-009600. J Immunother Cancer. 2024. PMID: 39313308 Free PMC article.

6

TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition.

Xu L, Xuan H, He W, Zhang L, Huang M, Li K, Wen H, Xu H, Shi X. Xu L, et al. Nat Commun. 2023 Sep 2;14(1):5362. doi: 10.1038/s41467-023-41245-2. Nat Commun. 2023. PMID: 37660055 Free PMC article.

7

Systematic decomposition of sequence determinants governing CRISPR/Cas9 specificity.

Fu R, He W, Dou J, Villarreal OD, Bedford E, Wang H, Hou C, Zhang L, Wang Y, Ma D, Chen Y, Gao X, Depken M, Xu H. Fu R, et al. Nat Commun. 2022 Jan 25;13(1):474. doi: 10.1038/s41467-022-28028-x. Nat Commun. 2022. PMID: 35078987 Free PMC article.

8

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.

Zheng C, Wei Y, Zhang P, Xu L, Zhang Z, Lin K, Hou J, Lv X, Ding Y, Chiu Y, Jain A, Islam N, Malovannaya A, Wu Y, Ding F, Xu H, Sun M, Chen X, Chen Y. Zheng C, et al. J Clin Invest. 2023 Mar 1;133(5):e159940. doi: 10.1172/JCI159940. J Clin Invest. 2023. PMID: 36856111 Free PMC article.

9

Guide-specific loss of efficiency and off-target reduction with Cas9 variants.

Zhang L, He W, Fu R, Wang S, Chen Y, Xu H. Zhang L, et al. Nucleic Acids Res. 2023 Oct 13;51(18):9880-9893. doi: 10.1093/nar/gkad702. Nucleic Acids Res. 2023. PMID: 37615574 Free PMC article.

10

Systematic functional interrogation of human pseudogenes using CRISPRi.

Sun M, Wang Y, Zheng C, Wei Y, Hou J, Zhang P, He W, Lv X, Ding Y, Liang H, Hon CC, Chen X, Xu H, Chen Y. Sun M, et al. Genome Biol. 2021 Aug 23;22(1):240. doi: 10.1186/s13059-021-02464-2. Genome Biol. 2021. PMID: 34425866 Free PMC article.

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