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μMap Photoproximity Labeling Enables Small Molecule Binding Site Mapping.
Huth SW, Oakley JV, Seath CP, Geri JB, Trowbridge AD, Parker DL Jr, Rodriguez-Rivera FP, Schwaid AG, Ramil C, Ryu KA, White CH, Fadeyi OO, Oslund RC, MacMillan DWC. Huth SW, et al. J Am Chem Soc. 2023 Aug 2;145(30):16289-16296. doi: 10.1021/jacs.3c03325. Epub 2023 Jul 20. J Am Chem Soc. 2023. PMID: 37471577 Free PMC article.
Deoxytrifluoromethylation of Alcohols.
Intermaggio NE, Millet A, Davis DL, MacMillan DWC. Intermaggio NE, et al. J Am Chem Soc. 2022 Jul 13;144(27):11961-11968. doi: 10.1021/jacs.2c04807. Epub 2022 Jul 5. J Am Chem Soc. 2022. PMID: 35786873 Free PMC article.
Current advances in photocatalytic proximity labeling.
Knutson SD, Buksh BF, Huth SW, Morgan DC, MacMillan DWC. Knutson SD, et al. Cell Chem Biol. 2024 Jun 20;31(6):1145-1161. doi: 10.1016/j.chembiol.2024.03.012. Epub 2024 Apr 24. Cell Chem Biol. 2024. PMID: 38663396 Review.
Late-Stage C(sp3)-H Methylation of Drug Molecules.
Mao E, MacMillan DWC. Mao E, et al. J Am Chem Soc. 2023 Feb 8;145(5):2787-2793. doi: 10.1021/jacs.2c13396. Epub 2023 Jan 25. J Am Chem Soc. 2023. PMID: 36696091 Free PMC article.
Copper-mediated synthesis of drug-like bicyclopentanes.
Zhang X, Smith RT, Le C, McCarver SJ, Shireman BT, Carruthers NI, MacMillan DWC. Zhang X, et al. Nature. 2020 Apr;580(7802):220-226. doi: 10.1038/s41586-020-2060-z. Epub 2020 Feb 17. Nature. 2020. PMID: 32066140 Free PMC article.
μMap-Red: Proximity Labeling by Red Light Photocatalysis.
Buksh BF, Knutson SD, Oakley JV, Bissonnette NB, Oblinsky DG, Schwoerer MP, Seath CP, Geri JB, Rodriguez-Rivera FP, Parker DL, Scholes GD, Ploss A, MacMillan DWC. Buksh BF, et al. J Am Chem Soc. 2022 Apr 13;144(14):6154-6162. doi: 10.1021/jacs.2c01384. Epub 2022 Apr 1. J Am Chem Soc. 2022. PMID: 35363468 Free PMC article.
Metallaphotoredox: The Merger of Photoredox and Transition Metal Catalysis.
Chan AY, Perry IB, Bissonnette NB, Buksh BF, Edwards GA, Frye LI, Garry OL, Lavagnino MN, Li BX, Liang Y, Mao E, Millet A, Oakley JV, Reed NL, Sakai HA, Seath CP, MacMillan DWC. Chan AY, et al. Chem Rev. 2022 Jan 26;122(2):1485-1542. doi: 10.1021/acs.chemrev.1c00383. Epub 2021 Nov 18. Chem Rev. 2022. PMID: 34793128 Review.
47 results