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SETD1B mutations confer apoptosis resistance and BCL2 independence in B cell lymphoma.
Portelinha A, Wang S, Parsa S, Jiang M, Gorelick AN, Mohanty S, Sharma S, de Stanchina E, Berishaj M, Zhao C, Heward J, Aryal NK, Tavana O, Wen J, Fitzgibbon J, Dogan A, Younes A, Melnick AM, Wendel HG. Portelinha A, et al. J Exp Med. 2024 Oct 7;221(10):e20231143. doi: 10.1084/jem.20231143. Epub 2024 Sep 5. J Exp Med. 2024. PMID: 39235528
Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules.
Singh K, Lin J, Lecomte N, Mohan P, Gokce A, Sanghvi VR, Jiang M, Grbovic-Huezo O, Burčul A, Stark SG, Romesser PB, Chang Q, Melchor JP, Beyer RK, Duggan M, Fukase Y, Yang G, Ouerfelli O, Viale A, de Stanchina E, Stamford AW, Meinke PT, Rätsch G, Leach SD, Ouyang Z, Wendel HG. Singh K, et al. Cancer Res. 2021 Apr 15;81(8):2002-2014. doi: 10.1158/0008-5472.CAN-20-2929. Epub 2021 Feb 25. Cancer Res. 2021. PMID: 33632898 Free PMC article.
A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes.
Salloum D, Singh K, Davidson NR, Cao L, Kuo D, Sanghvi VR, Jiang M, Lafoz MT, Viale A, Ratsch G, Wendel HG. Salloum D, et al. J Immunol. 2022 Sep 15;209(6):1189-1199. doi: 10.4049/jimmunol.2100537. Epub 2022 Aug 24. J Immunol. 2022. PMID: 36002234 Free PMC article.
eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer.
Boyer JA, Sharma M, Dorso MA, Mai N, Amor C, Reiter JM, Kannan R, Gadal S, Xu J, Miele M, Li Z, Chen X, Chang Q, Pareja F, Worland S, Warner D, Sperry S, Chiang GG, Thompson PA, Yang G, Ouerfelli O, de Stanchina E, Wendel HG, Rosen EY, Chandarlapaty S, Rosen N. Boyer JA, et al. bioRxiv [Preprint]. 2024 May 11:2024.05.08.593195. doi: 10.1101/2024.05.08.593195. bioRxiv. 2024. PMID: 38766126 Free PMC article. Preprint.
Targeting lysine demethylase 5 (KDM5) in mantle cell lymphoma.
Xu D, Bewicke-Copley F, Close K, Okosun J, Gale RP, Apperley J, Weinstock DM, Wendel HG, Fitzgibbon J. Xu D, et al. Blood Cancer J. 2024 Feb 13;14(1):29. doi: 10.1038/s41408-024-00999-8. Blood Cancer J. 2024. PMID: 38351059 Free PMC article. No abstract available.
12 results