R35 CA210036/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	2
2018	3
2020	6
2021	2
2022	6
2023	5
2024	5
2025	0

1

de Lange T. de Lange T. Annu Rev Genet. 2018 Nov 23;52:223-247. doi: 10.1146/annurev-genet-032918-021921. Epub 2018 Sep 12. Annu Rev Genet. 2018. PMID: 30208292 Review.

2

POT1 recruits and regulates CST-Polα/primase at human telomeres.

Cai SW, Takai H, Zaug AJ, Dilgen TC, Cech TR, Walz T, de Lange T. Cai SW, et al. Cell. 2024 Jul 11;187(14):3638-3651.e18. doi: 10.1016/j.cell.2024.05.002. Epub 2024 Jun 4. Cell. 2024. PMID: 38838667 Free article.

3

ATR blocks telomerase from converting DNA breaks into telomeres.

Kinzig CG, Zakusilo G, Takai KK, Myler LR, de Lange T. Kinzig CG, et al. Science. 2024 Feb 16;383(6684):763-770. doi: 10.1126/science.adg3224. Epub 2024 Feb 15. Science. 2024. PMID: 38359122 Free PMC article.

4

CST-polymerase α-primase solves a second telomere end-replication problem.

Takai H, Aria V, Borges P, Yeeles JTP, de Lange T. Takai H, et al. Nature. 2024 Mar;627(8004):664-670. doi: 10.1038/s41586-024-07137-1. Epub 2024 Feb 28. Nature. 2024. PMID: 38418884 Free PMC article.

5

CST-Polα/Primase: the second telomere maintenance machine.

Cai SW, de Lange T. Cai SW, et al. Genes Dev. 2023 Jul 1;37(13-14):555-569. doi: 10.1101/gad.350479.123. Epub 2023 Jul 26. Genes Dev. 2023. PMID: 37495394 Free PMC article. Review.

6

DNA-PK and the TRF2 iDDR inhibit MRN-initiated resection at leading-end telomeres.

Myler LR, Toia B, Vaughan CK, Takai K, Matei AM, Wu P, Paull TT, de Lange T, Lottersberger F. Myler LR, et al. Nat Struct Mol Biol. 2023 Sep;30(9):1346-1356. doi: 10.1038/s41594-023-01072-x. Epub 2023 Aug 31. Nat Struct Mol Biol. 2023. PMID: 37653239 Free PMC article.

7

53BP1: a DSB escort.

Mirman Z, de Lange T. Mirman Z, et al. Genes Dev. 2020 Jan 1;34(1-2):7-23. doi: 10.1101/gad.333237.119. Genes Dev. 2020. PMID: 31896689 Free PMC article. Review.

8

CST/Polα/primase-mediated fill-in synthesis at DSBs.

Mirman Z, Cai S, de Lange T. Mirman Z, et al. Cell Cycle. 2023 Feb;22(4):379-389. doi: 10.1080/15384101.2022.2123886. Epub 2022 Oct 7. Cell Cycle. 2023. PMID: 36205622 Free PMC article.

9

Chromothripsis and telomere crisis: engines of genome instability.

Dewhurst SM. Dewhurst SM. Curr Opin Genet Dev. 2020 Feb;60:41-47. doi: 10.1016/j.gde.2020.02.009. Epub 2020 Mar 6. Curr Opin Genet Dev. 2020. PMID: 32151946 Free PMC article. Review.

10

Most large structural variants in cancer genomes can be detected without long reads.

Choo ZN, Behr JM, Deshpande A, Hadi K, Yao X, Tian H, Takai K, Zakusilo G, Rosiene J, Da Cruz Paula A, Weigelt B, Setton J, Riaz N, Powell SN, Busam K, Shoushtari AN, Ariyan C, Reis-Filho J, de Lange T, Imieliński M. Choo ZN, et al. Nat Genet. 2023 Dec;55(12):2139-2148. doi: 10.1038/s41588-023-01540-6. Epub 2023 Nov 9. Nat Genet. 2023. PMID: 37945902 Free PMC article.

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