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Page 1
Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity.
Shenoy AT, Lyon De Ana C, Arafa EI, Salwig I, Barker KA, Korkmaz FT, Ramanujan A, Etesami NS, Soucy AM, Martin IMC, Tilton BR, Hinds A, Goltry WN, Kathuria H, Braun T, Jones MR, Quinton LJ, Belkina AC, Mizgerd JP. Shenoy AT, et al. Nat Commun. 2021 Oct 5;12(1):5834. doi: 10.1038/s41467-021-26045-w. Nat Commun. 2021. PMID: 34611166 Free PMC article.
GL7 ligand expression defines a novel subset of CD4+ TRM cells in lungs recovered from pneumococcus.
Lyon De Ana C, Shenoy AT, Barker KA, Arafa EI, Etesami NS, Korkmaz FT, Soucy AM, Breen MP, Martin IMC, Tilton BR, Devarajan P, Crossland NA, Pihl RMF, Goltry WN, Belkina AC, Jones MR, Quinton LJ, Mizgerd JP. Lyon De Ana C, et al. Mucosal Immunol. 2023 Oct;16(5):699-710. doi: 10.1016/j.mucimm.2023.07.004. Epub 2023 Sep 14. Mucosal Immunol. 2023. PMID: 37604254 Free PMC article.
B cells in the pneumococcus-infected lung are heterogeneous and require CD4+ T cell help including CD40L to become resident memory B cells.
Etesami NS, Barker KA, Shenoy AT, De Ana CL, Arafa EI, Grifno GN, Matschulat AM, Vannini ME, Pihl RMF, Breen MP, Soucy AM, Goltry WN, Ha CT, Betsuyaku H, Browning JL, Varelas X, Traber KE, Jones MR, Quinton LJ, Maglione PJ, Nia HT, Belkina AC, Mizgerd JP. Etesami NS, et al. Front Immunol. 2024 Apr 23;15:1382638. doi: 10.3389/fimmu.2024.1382638. eCollection 2024. Front Immunol. 2024. PMID: 38715601 Free PMC article.
Lung-resident memory B cells protect against bacterial pneumonia.
Barker KA, Etesami NS, Shenoy AT, Arafa EI, Lyon de Ana C, Smith NM, Martin IM, Goltry WN, Barron AM, Browning JL, Kathuria H, Belkina AC, Guillon A, Zhong X, Crossland NA, Jones MR, Quinton LJ, Mizgerd JP. Barker KA, et al. J Clin Invest. 2021 Jun 1;131(11):e141810. doi: 10.1172/JCI141810. J Clin Invest. 2021. PMID: 34060477 Free PMC article.
Pneumonia recovery reprograms the alveolar macrophage pool.
Guillon A, Arafa EI, Barker KA, Belkina AC, Martin I, Shenoy AT, Wooten AK, Lyon De Ana C, Dai A, Labadorf A, Hernandez Escalante J, Dooms H, Blasco H, Traber KE, Jones MR, Quinton LJ, Mizgerd JP. Guillon A, et al. JCI Insight. 2020 Feb 27;5(4):e133042. doi: 10.1172/jci.insight.133042. JCI Insight. 2020. PMID: 31990682 Free PMC article.
Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care. NHLBI Working Group Report.
Semler MW, Bernard GR, Aaron SD, Angus DC, Biros MH, Brower RG, Calfee CS, Colantuoni EA, Ferguson ND, Gong MN, Hopkins RO, Hough CL, Iwashyna TJ, Levy BD, Martin TR, Matthay MA, Mizgerd JP, Moss M, Needham DM, Self WH, Seymour CW, Stapleton RD, Thompson BT, Wunderink RG, Aggarwal NR, Reineck LA. Semler MW, et al. Am J Respir Crit Care Med. 2020 Aug 15;202(4):511-523. doi: 10.1164/rccm.201908-1595WS. Am J Respir Crit Care Med. 2020. PMID: 32150460 Free PMC article.
SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19.
Serrano GE, Walker JE, Tremblay C, Piras IS, Huentelman MJ, Belden CM, Goldfarb D, Shprecher D, Atri A, Adler CH, Shill HA, Driver-Dunckley E, Mehta SH, Caselli R, Woodruff BK, Haarer CF, Ruhlen T, Torres M, Nguyen S, Schmitt D, Rapscak SZ, Bime C, Peters JL, Alevritis E, Arce RA, Glass MJ, Vargas D, Sue LI, Intorcia AJ, Nelson CM, Oliver J, Russell A, Suszczewicz KE, Borja CI, Cline MP, Hemmingsen SJ, Qiji S, Hobgood HM, Mizgerd JP, Sahoo MK, Zhang H, Solis D, Montine TJ, Berry GJ, Reiman EM, Röltgen K, Boyd SD, Pinsky BA, Zehnder JL, Talbot P, Desforges M, DeTure M, Dickson DW, Beach TG. Serrano GE, et al. J Neuropathol Exp Neurol. 2022 Aug 16;81(9):666-695. doi: 10.1093/jnen/nlac056. J Neuropathol Exp Neurol. 2022. PMID: 35818336 Free PMC article.
Increased Risk of Autopsy-Proven Pneumonia with Sex, Season and Neurodegenerative Disease.
Beach TG, Russell A, Sue LI, Intorcia AJ, Glass MJ, Walker JE, Arce R, Nelson CM, Hidalgo T, Chiarolanza G, Mariner M, Scroggins A, Pullen J, Souders L, Sivananthan K, Carter N, Saxon-LaBelle M, Hoffman B, Garcia A, Callan M, Fornwalt BE, Carew J, Filon J, Cutler B, Papa J, Curry JR, Oliver J, Shprecher D, Atri A, Belden C, Shill HA, Driver-Dunckley E, Mehta SH, Adler CH, Haarer CF, Ruhlen T, Torres M, Nguyen S, Schmitt D, Fietz M, Lue LF, Walker DG, Mizgerd JP, Serrano GE. Beach TG, et al. medRxiv [Preprint]. 2021 Jan 8:2021.01.07.21249410. doi: 10.1101/2021.01.07.21249410. medRxiv. 2021. PMID: 33442709 Free PMC article. Preprint.
16 results