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Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging.
Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Castro Torres T, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, Vega M, Mehta HH, Thorwald MA, Crews P, Vermulst M, Garcia G, Johnson TA, Higuchi-Sanabria R. Dutta N, et al. bioRxiv [Preprint]. 2023 Nov 27:2023.11.27.568896. doi: 10.1101/2023.11.27.568896. bioRxiv. 2023. PMID: 38077060 Free PMC article. Preprint.
Growth on stiffer substrates impacts animal health and longevity in C. elegans.
Oorloff M, Hruby A, Averbukh M, Alcala A, Dutta N, Minor C, Castro Torres T, Moaddeli D, Vega M, Kim J, Bong A, Coakley AJ, Hicks D, Wang J, Wang T, Hoang S, Tharp KM, Garcia G, Higuchi-Sanabria R. Oorloff M, et al. PLoS One. 2024 Sep 12;19(9):e0302673. doi: 10.1371/journal.pone.0302673. eCollection 2024. PLoS One. 2024. PMID: 39264947 Free PMC article.
Mechanical stress through growth on stiffer substrates impacts animal health and longevity in C. elegans.
Oorloff M, Hruby A, Averbukh M, Alcala A, Dutta N, Torres TC, Moaddeli D, Vega M, Kim J, Bong A, Coakley AJ, Hicks D, Wang J, Wang T, Hoang S, Tharp KM, Garcia G, Higuchi-Sanabria R. Oorloff M, et al. bioRxiv [Preprint]. 2024 Apr 12:2024.04.11.589121. doi: 10.1101/2024.04.11.589121. bioRxiv. 2024. Update in: PLoS One. 2024 Sep 12;19(9):e0302673. doi: 10.1371/journal.pone.0302673 PMID: 38645203 Free PMC article. Updated. Preprint.
Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging.
Dutta N, Gerke JA, Odron SF, Morris JD, Hruby A, Kim J, Torres TC, Shemtov SJ, Clarke JG, Chang MC, Shaghasi H, Ray MN, Averbukh M, Hoang S, Oorloff M, Alcala A, Vega M, Mehta HH, Thorwald MA, Crews P, Vermulst M, Garcia G, Johnson TA, Higuchi-Sanabria R. Dutta N, et al. Geroscience. 2024 Dec;46(6):6009-6028. doi: 10.1007/s11357-024-01144-w. Epub 2024 Apr 3. Geroscience. 2024. PMID: 38570396 Free PMC article.