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Page 1
Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression.
Schmiedel BJ, Singh D, Madrigal A, Valdovino-Gonzalez AG, White BM, Zapardiel-Gonzalo J, Ha B, Altay G, Greenbaum JA, McVicker G, Seumois G, Rao A, Kronenberg M, Peters B, Vijayanand P. Schmiedel BJ, et al. Cell. 2018 Nov 29;175(6):1701-1715.e16. doi: 10.1016/j.cell.2018.10.022. Epub 2018 Nov 15. Cell. 2018. PMID: 30449622 Free PMC article. Clinical Trial.
Transcriptomes and metabolism define mouse and human MAIT cell populations.
Chandra S, Ascui G, Riffelmacher T, Chawla A, Ramírez-Suástegui C, Castelan VC, Seumois G, Simon H, Murray MP, Seo GY, Premlal ALR, Schmiedel B, Verstichel G, Li Y, Lin CH, Greenbaum J, Lamberti J, Murthy R, Nigro J, Cheroutre H, Ottensmeier CH, Hedrick SM, Lu LF, Vijayanand P, Kronenberg M. Chandra S, et al. Sci Immunol. 2023 Nov 10;8(89):eabn8531. doi: 10.1126/sciimmunol.abn8531. Epub 2023 Nov 10. Sci Immunol. 2023. PMID: 37948512 Free PMC article.
Single-cell eQTL analysis of activated T cell subsets reveals activation and cell type-dependent effects of disease-risk variants.
Schmiedel BJ, Gonzalez-Colin C, Fajardo V, Rocha J, Madrigal A, Ramírez-Suástegui C, Bhattacharyya S, Simon H, Greenbaum JA, Peters B, Seumois G, Ay F, Chandra V, Vijayanand P. Schmiedel BJ, et al. Sci Immunol. 2022 Feb 25;7(68):eabm2508. doi: 10.1126/sciimmunol.abm2508. Epub 2022 Feb 25. Sci Immunol. 2022. PMID: 35213211 Free PMC article.
Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.
Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. Pagadala M, et al. Nat Commun. 2023 May 12;14(1):2744. doi: 10.1038/s41467-023-38271-5. Nat Commun. 2023. PMID: 37173324 Free PMC article.
Recipient APOL1 risk alleles associate with death-censored renal allograft survival and rejection episodes.
Zhang Z, Sun Z, Fu J, Lin Q, Banu K, Chauhan K, Planoutene M, Wei C, Salem F, Yi Z, Liu R, Cravedi P, Cheng H, Hao K, O'Connell PJ, Ishibe S, Zhang W, Coca SG, Gibson IW, Colvin RB, He JC, Heeger PS, Murphy B, Menon MC. Zhang Z, et al. J Clin Invest. 2021 Nov 15;131(22):e146643. doi: 10.1172/JCI146643. J Clin Invest. 2021. PMID: 34499625 Free PMC article.
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