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Base-modified thymidines capable of terminating DNA synthesis are novel bioactive compounds with activity in cancer cells.
Borland KM, AbdulSalam SF, Solivio MJ, Burke MP, Wolfkiel PR, Lawson SM, Stockman CA, Andersen JM, Smith S, Tolstolutskaya JN, Gurjar PN, Bercz AP, Merino EJ, Litosh VA. Borland KM, et al. Bioorg Med Chem. 2015 Apr 15;23(8):1869-81. doi: 10.1016/j.bmc.2015.01.057. Epub 2015 Feb 14. Bioorg Med Chem. 2015. PMID: 25778768 Free PMC article.
A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.
Derrick JS, Kerr RA, Nam Y, Oh SB, Lee HJ, Earnest KG, Suh N, Peck KL, Ozbil M, Korshavn KJ, Ramamoorthy A, Prabhakar R, Merino EJ, Shearer J, Lee JY, Ruotolo BT, Lim MH. Derrick JS, et al. J Am Chem Soc. 2015 Nov 25;137(46):14785-97. doi: 10.1021/jacs.5b10043. Epub 2015 Nov 17. J Am Chem Soc. 2015. PMID: 26575890 Free PMC article.