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Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain.
Biosci Rep. 2018 Jul 6;38(4):BSR20180231. doi: 10.1042/BSR20180231. Print 2018 Aug 31.
Biosci Rep. 2018.
PMID: 29472314
Free PMC article.
A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR.
Cushing PR, Vouilleme L, Pellegrini M, Boisguerin P, Madden DR.
Cushing PR, et al.
Angew Chem Int Ed Engl. 2010 Dec 17;49(51):9907-11. doi: 10.1002/anie.201005585.
Angew Chem Int Ed Engl. 2010.
PMID: 21105033
Free PMC article.
No abstract available.
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