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Ypt/Rab GTPases and their TRAPP GEFs at the Golgi.
Lipatova Z, Segev N. Lipatova Z, et al. FEBS Lett. 2019 Sep;593(17):2488-2500. doi: 10.1002/1873-3468.13574. Epub 2019 Aug 21. FEBS Lett. 2019. PMID: 31400292 Free PMC article. Review.
TRAPPing a neurological disorder: from yeast to humans.
Lipatova Z, Van Bergen N, Stanga D, Sacher M, Christodoulou J, Segev N. Lipatova Z, et al. Autophagy. 2020 May;16(5):965-966. doi: 10.1080/15548627.2020.1736873. Epub 2020 Mar 6. Autophagy. 2020. PMID: 32116085 Free PMC article.
A Rab5 GTPase module is important for autophagosome closure.
Zhou F, Zou S, Chen Y, Lipatova Z, Sun D, Zhu X, Li R, Wu Z, You W, Cong X, Zhou Y, Xie Z, Gyurkovska V, Liu Y, Li Q, Li W, Cheng J, Liang Y, Segev N. Zhou F, et al. PLoS Genet. 2017 Sep 21;13(9):e1007020. doi: 10.1371/journal.pgen.1007020. eCollection 2017 Sep. PLoS Genet. 2017. PMID: 28934205 Free PMC article.
Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability.
Van Bergen NJ, Guo Y, Al-Deri N, Lipatova Z, Stanga D, Zhao S, Murtazina R, Gyurkovska V, Pehlivan D, Mitani T, Gezdirici A, Antony J, Collins F, Willis MJH, Coban Akdemir ZH, Liu P, Punetha J, Hunter JV, Jhangiani SN, Fatih JM, Rosenfeld JA, Posey JE, Gibbs RA, Karaca E, Massey S, Ranasinghe TG, Sleiman P, Troedson C, Lupski JR, Sacher M, Segev N, Hakonarson H, Christodoulou J. Van Bergen NJ, et al. Brain. 2020 Jan 1;143(1):112-130. doi: 10.1093/brain/awz374. Brain. 2020. PMID: 31794024 Free PMC article.