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A mutant light-chain ferritin that causes neurodegeneration has enhanced propensity toward oxidative damage.
Free Radic Biol Med. 2012 May 1;52(9):1692-7. doi: 10.1016/j.freeradbiomed.2012.02.015. Epub 2012 Feb 17.
Free Radic Biol Med. 2012.
PMID: 22348978
Free PMC article.
Iron loading-induced aggregation and reduction of iron incorporation in heteropolymeric ferritin containing a mutant light chain that causes neurodegeneration.
Muhoberac BB, Baraibar MA, Vidal R.
Muhoberac BB, et al.
Biochim Biophys Acta. 2011 Apr;1812(4):544-8. doi: 10.1016/j.bbadis.2010.10.010. Epub 2010 Oct 26.
Biochim Biophys Acta. 2011.
PMID: 21029774
Free PMC article.
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