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Lower Airway Dysbiosis Augments Lung Inflammatory Injury in Mild-to-Moderate Chronic Obstructive Pulmonary Disease.
Sulaiman I, Wu BG, Chung M, Isaacs B, Tsay JJ, Holub M, Barnett CR, Kwok B, Kugler MC, Natalini JG, Singh S, Li Y, Schluger R, Carpenito J, Collazo D, Perez L, Kyeremateng Y, Chang M, Campbell CD, Hansbro PM, Oppenheimer BW, Berger KI, Goldring RM, Koralov SB, Weiden MD, Xiao R, D'Armiento J, Clemente JC, Ghedin E, Segal LN. Sulaiman I, et al. Am J Respir Crit Care Med. 2023 Nov 15;208(10):1101-1114. doi: 10.1164/rccm.202210-1865OC. Am J Respir Crit Care Med. 2023. PMID: 37677136 Free PMC article.
Pathobiological signatures of dysbiotic lung injury in pediatric patients undergoing stem cell transplantation.
Zinter MS, Dvorak CC, Mayday MY, Reyes G, Simon MR, Pearce EM, Kim H, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Godder K, Duncan CN, Lalefar NR, Kreml EM, Hume JR, Abdel-Azim H, Hurley C, Cuvelier GDE, Keating AK, Qayed M, Killinger JS, Fitzgerald JC, Hanna R, Mahadeo KM, Quigg TC, Satwani P, Castillo P, Gertz SJ, Moore TB, Hanisch B, Abdel-Mageed A, Phelan R, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Sulaiman I, Segal LN, Versluys BA, Lindemans CA, Boelens JJ, DeRisi JL; Pediatric Transplantation and Cell Therapy Consortium. Zinter MS, et al. Nat Med. 2024 Jul;30(7):1982-1993. doi: 10.1038/s41591-024-02999-4. Epub 2024 May 23. Nat Med. 2024. PMID: 38783139 Free PMC article.
Longitudinal Lower Airway Microbial Signatures of Acute Cellular Rejection in Lung Transplantation.
Natalini JG, Wong KK, Nelson NC, Wu BG, Rudym D, Lesko MB, Qayum S, Lewis TC, Wong A, Chang SH, Chan JCY, Geraci TC, Li Y, Wang C, Li H, Pamar P, Schnier J, Mahoney IJ, Malik T, Darawshy F, Sulaiman I, Kugler MC, Singh R, Collazo DE, Chang M, Patel S, Kyeremateng Y, McCormick C, Barnett CR, Tsay JJ, Brosnahan SB, Singh S, Pass HI, Angel LF, Segal LN. Natalini JG, et al. Am J Respir Crit Care Med. 2024 Jun 15;209(12):1463-1476. doi: 10.1164/rccm.202309-1551OC. Am J Respir Crit Care Med. 2024. PMID: 38358857
Pulmonary microbiome and transcriptome signatures reveal distinct pathobiologic states associated with mortality in two cohorts of pediatric stem cell transplant patients.
Zinter MS, Dvorak CC, Mayday MY, Reyes G, Simon MR, Pearce EM, Kim H, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Godder K, Duncan CN, Lalefar NR, Kreml EM, Hume JR, Abdel-Azim H, Hurley C, Cuvelier GDE, Keating AK, Qayed M, Killinger JS, Fitzgerald JC, Hanna R, Mahadeo KM, Quigg TC, Satwani P, Castillo P, Gertz SJ, Moore TB, Hanisch B, Abdel-Mageed A, Phelan R, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Sulaiman I, Segal LN, Versluys BA, Lindemans CA, Boelens JJ, DeRisi JL; Pediatric Transplantation and Cell Therapy Consortium. Zinter MS, et al. medRxiv [Preprint]. 2023 Nov 29:2023.11.29.23299130. doi: 10.1101/2023.11.29.23299130. medRxiv. 2023. PMID: 38077035 Free PMC article. Preprint.
Impaired immune responses in the airways are associated with poor outcome in critically ill COVID-19 patients.
Barnett CR, Krolikowski K, Postelnicu R, Mukherjee V, Sulaiman I, Chung M, Angel L, Tsay JJ, Wu BG, Yeung ST, Duerr R, Desvignes L, Khanna K, Li Y, Schluger R, Rafeq S, Collazo D, Kyeremateng Y, Amoroso N, Pradhan D, Das S, Evans L, Uyeki TM, Ghedin E, Silverman GJ, Segal LN, Brosnahan SB. Barnett CR, et al. ERJ Open Res. 2024 Jul 8;10(4):00789-2023. doi: 10.1183/23120541.00789-2023. eCollection 2024 Jul. ERJ Open Res. 2024. PMID: 38978558 Free PMC article.