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A subcutaneous adipose tissue-liver signalling axis controls hepatic gluconeogenesis.
Reilly SM, Ahmadian M, Zamarron BF, Chang L, Uhm M, Poirier B, Peng X, Krause DM, Korytnaya E, Neidert A, Liddle C, Yu RT, Lumeng CN, Oral EA, Downes M, Evans RM, Saltiel AR. Reilly SM, et al. Nat Commun. 2015 Jan 12;6:6047. doi: 10.1038/ncomms7047. Nat Commun. 2015. PMID: 25581158 Free PMC article. Clinical Trial.
Inhibition of IKKɛ and TBK1 Improves Glucose Control in a Subset of Patients with Type 2 Diabetes.
Oral EA, Reilly SM, Gomez AV, Meral R, Butz L, Ajluni N, Chenevert TL, Korytnaya E, Neidert AH, Hench R, Rus D, Horowitz JF, Poirier B, Zhao P, Lehmann K, Jain M, Yu R, Liddle C, Ahmadian M, Downes M, Evans RM, Saltiel AR. Oral EA, et al. Cell Metab. 2017 Jul 5;26(1):157-170.e7. doi: 10.1016/j.cmet.2017.06.006. Cell Metab. 2017. PMID: 28683283 Free PMC article. Clinical Trial.